Tag: Antagonist

For research use only. We do not sell to patients. NIDA-41020 CAS No. : 502486-89-7 Biological Activity：NIDA-41020 is a potent and selective cannabinoid receptor 1(CB1) antagonist with a Ki of 4.1 nM. NIDA-41020 was designed as a potential radioligand for use in positron emission tomography (PET). Research Area：Neurological Disease Targets：Cannabinoid Receptor Related Small Molecules:Pregnenolone monosulfate […]

For research use only. We do not sell to patients. OT antagonist 1 demethyl derivative Biological Activity：OT antagonist 1 demethyl derivative is the demethyl derivative of OT antagonist 1. OT antagonist 1 (Compound 4) is a potent, selective Oxytocin antagonist with a Ki of 50 nM. Research Area：Endocrinology Targets：Oxytocin Receptor Related Small Molecules:L-368,899 hydrochloride;L-372662;L-371,257;Epelsiban;OT antagonist […]

For research use only. We do not sell to patients. Ro 46-8443 CAS No. : 175556-12-4 Biological Activity：Ro 46-8443 is the first non-peptide endothelin ETB receptor selective antagonist. Ro 46-8443 displays an at least 100-fold selectivity for ETB (IC50: 34-69 nM) over ETA receptors (IC50: 6800 nM)[2]. Research Area：Cardiovascular Disease Targets：Endothelin Receptor Related Screening Libraries:Bioactive […]

For research use only. We do not sell to patients. Homatropine Bromide CAS No. : 51-56-9 Biological Activity：Homatropine Bromide is an orally active muscarinic acetylcholine receptor antagonist and can be used as an anticholinergic agent. Research Area：Neurological Disease Targets：mAChR Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;GPCR/G […]

For research use only. We do not sell to patients. AZD2423 CAS No. : 1229603-37-5 Biological Activity：AZD2423 is a potent, selective, orally bioavailable, and non-competitive CCR2 chemokine receptor negative allosteric modulator. AZD2423 has an IC50 of 1.2 nM for CCR2 Ca2+ flux [2][3]. Research Area：Neurological Disease Targets：CCR Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound […]

For research use only. We do not sell to patients. L-Phenylalanine-d5 CAS No. : 56253-90-8 Biological Activity：L-Phenylalanine-d5 is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist […]

For research use only. We do not sell to patients. (S)-(-)-HA 966 CAS No. : 111821-58-0 Biological Activity：(S)-(-)-HA 966 ((-)-HA 966), a γ-Hydroxybutyrate-like agent, is weakly active as an NMDA-receptor antagonist. (S)-(-)-HA 966 possesses muscle relaxant action and prevents enhanced mesocorticolimbic dopamine metabolism and behavioral correlates of restraint stress, conditioned fear[2]. Research Area：Neurological Disease Targets：iGluR […]

For research use only. We do not sell to patients. NXT629 CAS No. : 1454925-59-7 Biological Activity：NXT629 is a potent, selective, and competitive PPAR-α antagonist, with an IC50 of 77 nM for human PPARα, shows high selectivity over other nuclear hormone receptor, such as PPARδ, PPARγ, ERβ, GR and TRβ, IC50s are 6.0, 15, 15.2, […]

For research use only. We do not sell to patients. SB-649868 CAS No. : 380899-24-1 Biological Activity：SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor antagonist (pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively). Research Area：Metabolic Disease|Endocrinology Targets：Orexin Receptor (OX Receptor) Related Small Molecules:MK-3697;JNJ-54717793;TCS-OX2-29;IPSU;Seltorexant hydrochloride;Orexin B, rat, […]

For research use only. We do not sell to patients. RS-601 CAS No. : 207987-59-5 Biological Activity：RS-601 is a novel leukotriene D4 (LTD4)/thromboxane A2 (TxA2) dual receptor antagonist, with antiasthmatic activities. Research Area：Inflammation/Immunology|Endocrinology Targets：Prostaglandin Receptor|Leukotriene Receptor Related Small Molecules:Pranlukast-d4;Omidenepag isopropyl;DG-041;8-Isoprostaglandin E2;BAY-6672;trans-Isoferulic acid;GSK-269984A;KMN-80;Verlukast-d6;SC 51089;p-Hydroxycinnamic acid;Pexopiprant;Dinoprost;Ablukast;Sulprostone;CP-96486;Prostaglandin E2;MK-886;CAY10471 Racemate;Fevipiprant;TG6-10-1;Cicaprost;BIIL-260 hydrochloride;ER-819762;MRE-269-d6 Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  […]