Tag: Antagonist

For research use only. We do not sell to patients. PA-9 CAS No. : 1436004-46-4 Biological Activity：PA-9 is a pituitary adenylate cyclase-activating polypeptide (PACAP) type I (PAC1) receptor antagonist. PA-9 dose dependently inhibits PACAP-induced cAMP elevation with an IC50 of 5.6 nM. PA-9 can be used for the research of neuropathic and/or inflammatory pain. Research […]

For research use only. We do not sell to patients. Pimethixene maleate CAS No. : 13187-06-9 Biological Activity：Pimethixene maleate is antihistamine and antiserotonergic compound, acts as an antimigraine agent. Pimethixene maleate is a highly potent antagonist of 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors, […]

For research use only. We do not sell to patients. PF-02413873 CAS No. : 936345-35-6 Biological Activity：PF-02413873 (PF-2413873) is a potent selective, fully competitive and orally active nonsteroidal progesterone receptor (PR) antagonist, with a Ki of 2.6 nM. PF-02413873 can block progesterone binding and PR nuclear translocation, and inhibit endometrial growth in vivo[2]. Research Area：Endocrinology […]

For research use only. We do not sell to patients. α-Conotoxin EI CAS No. : 170663-33-9 Biological Activity：α-Conotoxin EI is a selective nicotinic acetylcholine α1β1γδ receptor (nAChR) antagonist (IC50=187 nM) and an α3β4 receptor inhibitor. α-Conotoxin EI can block muscle and ganglionic receptors[2][3]. Research Area：Neurological Disease Targets：nAChR Related Small Molecules:Spinosad;Pyrantel;NS 9283;Myosmine-d4;Benzethonium chloride;Dihydro-β-erythroidine;A-867744;Catestatin;Asoxime dichloride;α7 nAchR-JAK2-STAT3 agonist […]

For research use only. We do not sell to patients. Roxatidine acetate CAS No. : 78628-28-1 Biological Activity：Roxatidine acetate is a potent, selective, competitive and orally active histamine H2-receptor antagonist. Roxatidine acetate has antisecretory potency against gastric acid secretion. Roxatidine acetate can also suppress inflammatory responses and can be used for gastric and duodenal ulcers […]

For research use only. We do not sell to patients. LY288513 CAS No. : 147523-65-7 Biological Activity：LY288513 is a selective non-peptide CCK-B receptor antagonist with an IC50 value of 16 nM. LY288513 produces an anxiolytic-like action in mice[2][3]. Research Area：Neurological Disease Targets：Cholecystokinin Receptor Related Small Molecules:Loxiglumide;Gastrin I, human;(Rac)-Sograzepide;Nastorazepide;Proglumide;Lorglumide sodium salt;Tarazepide;L-365260 hemihydrate;Mini Gastrin I, human TFA;CCK-B […]

For research use only. We do not sell to patients. L-771688 CAS No. : 200050-59-5 Biological Activity：L-771688 is a highly selective α1A-Adrenoceptor antagonist with a Ki of 0.43±0.02 nM. Research Area：Cancer|Endocrinology Targets：Adrenergic Receptor Related Small Molecules:Todralazine;ARC 239 dihydrochloride;Yohimbine;Glaucine;Salbutamol;BI-167107;Talibegron hydrochloride;Arotinolol;SR59230A;Higenamine hydrochloride;Navafenterol saccharinate;Isoprenaline hydrochloride;Bevantolol;Zilpaterol-d7;Ritanserin;A55453;Povafonidine;β3-AR agonist 1;Tulobuterol;AGN 192836;KUC-7322;Oxyfedrine;Urapidil hydrochloride;Detomidine hydrochloride;Oxprenolol-d7 hydrochloride;Nicergoline;Synephrine hemitartrate;ADRA1D receptor antagonist 1;Solabegron Trending products：Recombinant Proteins  […]

For research use only. We do not sell to patients. Ambrisentan CAS No. : 177036-94-1 Biological Activity：Ambrisentan is a selective ET type A receptor (ETAR) antagonist. Research Area：Cardiovascular Disease|Endocrinology Targets：Endothelin Receptor Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;FDA-Approved Drug Library;Drug Repurposing Compound Library;Anti-diabetic […]

For research use only. We do not sell to patients. MK-7246 CAS No. : 1218918-62-7 Biological Activity：MK-7246 is a potent and selective CRTH2 antagonist with a Ki of 2.5±0.5 nM. Research Area：Inflammation/Immunology|Endocrinology Targets：Prostaglandin Receptor Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Endocrinology Compound Library;Chemical Probe Library;Angiogenesis-Related Compound Library;Targeted Diversity Library; Related Small […]

For research use only. We do not sell to patients. R-7050 CAS No. : 303997-35-5 Biological Activity：R-7050 (TNF-α Antagonist III) is a tumor necrosis factor receptor (TNFR) antagonist with greater selectivity toward TNFα. Research Area：Cancer Targets：TNF Receptor Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound Library;Anti-Cancer Compound Library;Pyroptosis Compound Library;Angiogenesis-Related Compound Library;Targeted Diversity Library;Antidepressant […]