Tag: Antagonist

For research use only. We do not sell to patients. Zaltidine CAS No. : 85604-00-8 Biological Activity：Zaltidine(CP-57361) is a H2-receptor antagonist, which has the antisecretory action. IC50 Value: Target: H2 receptor in vitro: in vivo: In eight healthy male volunteers single oral doses of 5 mg, 25 mg and 100 mg produced dose-related inhibition of […]

For research use only. We do not sell to patients. γ-Linolenic acid ethyl ester CAS No. : 31450-14-3 Biological Activity：γ-Linolenic acid ethyl ester (Ethyl γ-linolenate) is a leukotriene B4 receptor 4 (LTB4) antagonist. Research Area：Inflammation/Immunology Targets：Leukotriene Receptor Related Small Molecules:Pranlukast-d4;Verlukast-d6;Ablukast;CP-96486;MK-886;BIIL-260 hydrochloride;Pranlukast;REV 5901;U-75302;RS-601;Tipelukast;LM-1484;RG-12525;Quinotolast sodium;Darbufelone mesylate;Chamazulene;11-​Keto-​beta-​boswellic acid;AS-35;Fiboflapon;BAY-u 9773;ONO4057;CP-96021 hydrochloride;Leukotriene B4;Amelubant Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  […]

For research use only. We do not sell to patients. HF51116 CAS No. : 2177311-29-2 Biological Activity：HF51116 is a potent antagonist of CXCR4. HF51116 strongly antagonizes SDF-1α-induced cell migration, calcium mobilization, and CXCR4 internalization. HF51116 inhibits HIV-1 infection via CXCR4. HF51116 has the potential for the research of HIV-1 infection, hematopoietic stem cell mobilization, and […]

For research use only. We do not sell to patients. Bosentan CAS No. : 147536-97-8 Biological Activity：Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively. Research Area：Cardiovascular Disease|Endocrinology Targets：Endothelin Receptor Related Screening Libraries:Drug Repurposing Compound Library […]

For research use only. We do not sell to patients. SB-399885 hydrochloride CAS No. : 402713-81-9 Biological Activity：SB-399885 hydrochloride is a 5-HT6 receptor antagonist. Research Area：Neurological Disease Targets：5-HT Receptor Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;Neurotransmitter Receptor Compound Library;Anti-Alzheimer’s Disease Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;5-HT Receptor Compound […]

For research use only. We do not sell to patients. Amlodipine-d4 besylate Biological Activity：Amlodipine-d4 (Amlodipine (benzenesulfonate)-d4) besylate is the deuterium labeled Amlodipine besylate. Amlodipine besylate (Amlodipine benzenesulfonate), an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine besylate […]

For research use only. We do not sell to patients. (αR,8aS)-GSK1614343 CAS No. : 1092476-84-0 Biological Activity：(αR,8aS)-GSK1614343 (compound 18a, d2) is a cyclized ghrelin antagonist with an pIC50 value of 8.4. (αR,8aS)-GSK1614343 shows a competitive antagonism of hGHSR1a with a mean pKb value of 8.06. Research Area：Inflammation/Immunology Targets：GHSR Related Small Molecules:Relamorelin acetate;Capromorelin Tartrate;BMS-604992 dihydrochloride;Macimorelin;TM-N1324;L-692585;Anamorelin hydrochloride;Obestatin(rat) […]

For research use only. We do not sell to patients. Relugolix CAS No. : 737789-87-6 Biological Activity：Relugolix (TAK-385) is a potent, orally active, nonpeptidic gonadotropin-releasing hormone (GnRH) antagonist. Relugolix possesses high affinity and potent antagonistic activity for human receptor (binding IC50=0.33 nM) and monkey receptor (IC50=0.32 nM) compared with TAK-013 (HY-100209). Relugolix is used for the […]

For research use only. We do not sell to patients. Cyclopentolate hydrochloride CAS No. : 5870-29-1 Biological Activity：Cyclopentolate (DL-Cyclopentolate) hydrochloride is an Atropine-like muscarinic receptors antagonist with a pKB value of 7.8 (on the circular ciliary muscle). Cyclopentolate hydrochloride is an anti-muscarinic agent commonly used in the ophthalmologic practice[2]. Research Area：Neurological Disease Targets：mAChR Related Screening […]

For research use only. We do not sell to patients. Falintolol, (Z)- CAS No. : 106401-52-9 Biological Activity：Falintolol, (Z)-, a new β-adrenergic antagonist, is characterized by the presence of an oxime function. Research Area：Endocrinology Targets：Adrenergic Receptor Related Small Molecules:Todralazine;ARC 239 dihydrochloride;Yohimbine;Glaucine;Salbutamol;BI-167107;Talibegron hydrochloride;Arotinolol;SR59230A;Higenamine hydrochloride;Navafenterol saccharinate;Isoprenaline hydrochloride;Bevantolol;Zilpaterol-d7;Ritanserin;A55453;Povafonidine;β3-AR agonist 1;Tulobuterol;AGN 192836;KUC-7322;Oxyfedrine;Urapidil hydrochloride;Detomidine hydrochloride;Oxprenolol-d7 hydrochloride;Nicergoline;Synephrine hemitartrate;ADRA1D receptor antagonist 1;Solabegron […]