Tag: Antagonist

For research use only. We do not sell to patients. Emicerfont CAS No. : 786701-13-1 Biological Activity：Emicerfont is a corticotropin-releasing factor type 1 (CRF1) receptor antagonist with an IC50 of 66 nM. Research Area：Neurological Disease|Endocrinology Targets：CRFR Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus; Related Small Molecules:Stresscopin-related peptide (human);Sauvagine;CRF(6-33)(human) TFA;NBI-27914;Urocortin […]

For research use only. We do not sell to patients. MRS2179 tetrasodium hydrate Biological Activity：MRS2179 tetrasodium hydrate is a competitive P2Y1 receptor antagonist, with a Kb of 102 nM and a pA2 of 6.99 for turkey P2Y1 receptor. MRS2179 tetrasodium hydrate is selective for P2Y1 over P2X1 (IC50=1.15 µM), P2X3 (12.9 µM), P2X2, P2X4, P2Y2, […]

For research use only. We do not sell to patients. BMS-193885 CAS No. : 186185-03-5 Biological Activity：BMS-193885 is a potent, selective, competitive, and brain penetrant neuropeptide Y1 receptor antagonist with a Ki of 3.3 nM, and has an IC50 of 5.9 nM for hY1, which displays > 100, > 160, > 160 and > 160-fold […]

For research use only. We do not sell to patients. PF-07258669 CAS No. : 2755890-53-8 Biological Activity：PF-07258669 is a melanocortin-4 receptor (MC4) antagonist. PF-07258669 can be used for the research of cachexia, anorexia, or anorexia nervosa. Research Area：Metabolic Disease|Neurological Disease Targets：Melanocortin Receptor Related Small Molecules:Bremelanotide;MSG606 TFA;Resomelagon;Dersimelagon;Adrenocorticotropic Hormone (ACTH) (1-39), rat TFA;Terrein;γ1-MSH TFA;SNT-207707;THIQ;ACTH (11-24) (acetate);JKC363 TFA;PG-931 […]

For research use only. We do not sell to patients. CPCCOEt CAS No. : 179067-99-3 Biological Activity：CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of metabotropic glutamate receptor 1b (mGluR1b)[2]. Research Area：Neurological Disease Targets：mGluR Related Small Molecules:LY3020371 hydrochloride;ZJ43;FPTQ;(S)-MCPG;mGluR2 modulator 1;VU6010572;Mavoglurant racemate;DFMTI;JNJ16259685;Auglurant;FITM;(-)-Camphoric acid;LY367385 hydrochloride;Cinnabarinic acid;LY379268;AZD 9272;mGluR2 antagonist 1;ABP688;FTIDC;MPPG;L-AP3;VU6001966;VU0155041 sodium;VU 0364439;trans-ACPD;AZD-8529 mesylate;VU 0357121;PHCCC;HexylHIBO;VU0650786 Trending products：Recombinant […]

For research use only. We do not sell to patients. Lavoltidine CAS No. : 76956-02-0 Biological Activity：Lavoltidine (Loxtidine) is an an orally active, irreversible and highly potent histamine H2-receptor antagonist. Lavoltidine strongly inhibits gastric acid secretion and also induces hypergastrinemia. Research Area：Cancer Targets：Histamine Receptor Related Small Molecules:Tripelennamine;Brompheniramine-d6 maleate;Samelisant;Chlorphenoxamine;H3 receptor-MO-1;Diphenhydramine;ABT-239;Ketotifen fumarate;Ranitidine;Cetirizine;Diphenylpyraline hydrochloride;Loratadine-d5;Phenyltoloxamine;Ritanserin;BMY-25271;FRG8701;Mecamylamine hydrochloride;Cimetidine sulfoxide;Brompheniramine maleate;Tecastemizole;Famotidine-13C,d3;Bromazine-d6 hydrochloride […]

For research use only. We do not sell to patients. [Nphe1]Nociceptin(1-13)NH2 CAS No. : 267234-08-2 Biological Activity：[Nphe1]Nociceptin(1-13)NH2, a novel nociceptin/orphanin FQ (NC) endogenous ligand, is a selective and competitive ociceptin receptor antagonist without any residual agonist activity. [Nphe1]nociceptin(1-13)NH2 binds selectively to recombinant nociceptin receptors (pKi=8.4) and antagonizes the inhibitory effects of nociceptin on cyclic AMP accumulation […]

For research use only. We do not sell to patients. Asoxime-d4 dichloride Biological Activity：Asoxime-d4 dichloride (HI-6-d4) is the deuterium labeled Asoxime dichloride. Asoxime dichloride (HI-6) is an antagonist to acetylcholine receptors (AChRs) including the nicotinic receptor, α7 nAChR. Asoxime dichloride involves in modulating immunity response. Asoxime dichloride (HI-6) can be used as an antigen and […]

For research use only. We do not sell to patients. RN-18 CAS No. : 431980-38-0 Biological Activity：RN-18 is a HIV-1 viral infectivity factor (HIV-1 Vif) inhibitor with an IC50 of 6 μM in nonpermissive H9 cells. Research Area：Infection Targets：HIV Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection Compound Library;Antiviral Compound Library; Related Small Molecules:HIV-1 TAT (48-60);Seletracetam lithium;HIV-IN-2;Triptonine […]

For research use only. We do not sell to patients. UFP-101 CAS No. : 849024-68-6 Biological Activity：UFP-101 is a potent, selective, and competitive antagonist of the NOP receptor, with a pKi of 10.24. UFP-101 displays >3000-fold selectivity over δ, μ and κ opioid receptors. UFP-101 shows antidepressant-like effect[2]. Research Area：Neurological Disease Targets：Opioid Receptor Related Small […]