Tag: Antagonist

For research use only. We do not sell to patients. ER-819762 CAS No. : 1155773-15-1 Biological Activity：ER-819762 is an orally active, highly selective prostaglandin E2 (PGE2) EP4 receptor antagonist with an EC50 of 70 nM against human EP4 receptor. ER-819762 can be used for rheumatoid arthritis research. Research Area：Inflammation/Immunology Targets：Prostaglandin Receptor Related Small Molecules:Omidenepag isopropyl;DG-041;8-Isoprostaglandin […]

For research use only. We do not sell to patients. Balovaptan CAS No. : 1228088-30-9 Biological Activity：Balovaptan (RG7314) is an orally available, selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors, and is used for the research of autism. Research Area：Neurological Disease|Endocrinology Targets：Vasopressin […]

For research use only. We do not sell to patients. ATL-801 CAS No. : 1000005-71-9 Biological Activity：ATL-801, an A2B receptor selective antagonist, ameliorates murine colitis. Research Area：Inflammation/Immunology Targets：Adenosine Receptor Related Small Molecules:MRS 1523;APNEA;MIPS521;Derenofylline;FSCPX;Theobromine-d3;Inosine-13C;Norisoboldine;N-0861 racemate;Xanthine amine congener dihydrochloride;LUF6096;A1/A3 AR antagonist 1;Istradefylline;Doxofylline-d6;A1AR antagonist 3;MRS1186;A2A/A3 AR antagonist-1;A2AAR/HDAC-IN-2;MRS-1191;MRS5698;GP531;Imaradenant;PSB-0788 Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent […]

For research use only. We do not sell to patients. MMG-11 quarterhydrate Biological Activity：MMG-11 quarterhydrate is a potent and selective human TLR2 antagonist with low cytotoxicity. MMG-11 quarterhydrate inhibits both TLR2/1 and TLR2/6 signaling with IC50s of 1.7 µM for Pam3CSK4-induced hTLR2/1 and 5.7 µM for Pam2CSK4-induced hTLR2/6 responses. Research Area：Inflammation/Immunology Targets：Toll-like Receptor (TLR) Related Screening Libraries:Bioactive […]

For research use only. We do not sell to patients. Ki16425 CAS No. : 355025-24-0 Biological Activity：Ki16425 (Debio 0719) is a subtype-selective, competitive antagonist of the EDG-family receptors, LPA1 and LPA3 with Kis of 0.34 μM and 0.93 μM, respectively. Ki16425 (Debio 0719) reduces the LPA-induced activation of p42/p44 MAPK[2]. Ki16425 can also inhibit LPA-induced […]

For research use only. We do not sell to patients. Pericyazine-d4 CAS No. : 1329836-72-7 Biological Activity：Pericyazine-d4 (Propericiazine-d4) is the deuterium labeled Pericyazine. Pericyazine (Propericiazine) is a first-generation antipsychotic agent that is used as an adjunct to the short-term management of severe anxiety states and psychosis. Pericyazine is a selective D2-dopamine receptor antagonist[2][3]. Pericyazine has […]

For research use only. We do not sell to patients. Reslizumab CAS No. : 241473-69-8 Biological Activity：Reslizumab (Sch 55700) is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma. Reslizumab is effective in neutralizing the function of IL-5. Reslizumab has high binding affinity for human IL-5, with KD values of 109 […]

For research use only. We do not sell to patients. Practolol CAS No. : 6673-35-4 Biological Activity：Practolol is a potent and selective β1-adrenergic receptor antagonist. Practolol can be used for the research of cardiac arrhythmias[2][3]. Research Area：Cardiovascular Disease Targets：Adrenergic Receptor Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;Anti-Cardiovascular Disease Compound Library;Neurotransmitter […]

For research use only. We do not sell to patients. 17-PA CAS No. : 694438-95-4 Biological Activity：17-PA is a selective antagonist of neurosteroid potentiation and direct gating of GABAA receptors. Research Area：Neurological Disease Targets：GABA Receptor Related Small Molecules:SKF89976A hydrochloride;mGAT-IN-1;Alpidem;FG8119;Valerenic acid;Picrotoxinin;Miltirone;Etifoxine-13C,d3;Adipiplon;Gabazine;Broflanilide;Fluxametamide;ONO-8590580;γ-Aminobutyric acid-d6;Ginsenoside Rc;Fipronil;p-Hydroxybenzaldehyde-13C;Lesogaberan hydrochloride;FG 7142;Isoguvacine hydrochloride;Guvacine ethyl ester;MRK-623;Rilmazafone;(-)-α-Pinene;Alpidem-d14 Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  […]

For research use only. We do not sell to patients. Diltiazem-d6 CAS No. : 1242184-41-3 Biological Activity：Diltiazem-d6 is the deuterium labeled Diltiazem. Diltiazem is an orally active L-type Ca2+ channel blocker, with antihypertensive and antiarrhythmic effects. Diltiazem can be used for the research of cardiac arrhythmia, hypertension, and angina pectoris[2][3]. Research Area：Cardiovascular Disease Targets：Calcium Channel […]