Tag: Antagonist

For research use only. We do not sell to patients. Galanin Receptor Ligand M35 TFA Biological Activity：Galanin Receptor Ligand M35 TFA is a high-affinity ligand and antagonist of galanin receptor (Kd=0.1 nM). Galanin Receptor Ligand M35 TFA exerts a Ki values of 0.11 and 2.0 nM for human galanin receptor type 1 and 2, respectively[2]. […]

For research use only. We do not sell to patients. Tocilizumab CAS No. : 375823-41-9 Biological Activity：Tocilizumab (Anti-Human IL6R, Humanized Antibody) is an anti-human interleukin-6 receptor (IL-6R) neutralizing antibody, prevents binding of IL-6 to the IL-6R, thereby inhibiting both classic and trans-signaling. Tocilizumab (Anti-Human IL6R, Humanized Antibody) can be used for the treatment of rheumatoid […]

For research use only. We do not sell to patients. Ambrisentan sodium CAS No. : 1386915-48-5 Biological Activity：Ambrisentan (BSF 208075) sodium is a selective and orally active ET type A receptor (ETAR) antagonist[2]. Research Area：Endocrinology|Cardiovascular Disease Targets：Endothelin Receptor Related Small Molecules:BQ-788;[Asn18] Endothelin-1, human;Endothelin-3, human, mouse, rabbit, rat TFA;IRL 2500;Sarafotoxin S6c;Sarafotoxin S6a;ANP (1-30), frog;IRL-1620 TFA;Tezosentan;ACT-373898;Ro 46-2005;Ro […]

For research use only. We do not sell to patients. A-987306 CAS No. : 1082954-71-9 Biological Activity：A-987306 is a potent and oral bioavailable histamine H4 antagonist, with Kis of 3.4 nM and 5.8 nM for rat H4, and human H4. A-987306 shows anti-inflammatory activity in mice peritonitis model. Research Area：Inflammation/Immunology Targets：Histamine Receptor Related Small Molecules:Tripelennamine;Brompheniramine-d6 […]

For research use only. We do not sell to patients. Androgen receptor antagonist 3 CAS No. : 353484-46-5 Biological Activity：Androgen receptor antagonist 3 (Compound C18) is an androgen receptor (AR) antagonist with an IC50 of 2.4 μM. Androgen receptor antagonist 3 shows anticancer activities. Research Area：Cancer Targets：Androgen Receptor Related Small Molecules:VPC-14449;AC-262536;GTx-007;Linuron-d6;MI-136;VPC-13789;RD162;ARD-2585;PF-998425;GSK-2881078;PROTAC AR Degrader-4;RU 58841;Triptophenolide;ARD-61;Dehydroisoandrosterone 3-acetate;Topilutamide;CSRM617 […]

For research use only. We do not sell to patients. Praeruptorin C CAS No. : 72463-77-5 Biological Activity：Praeruptorin C is a main bioactive constituent of Peucedanum praeruptorum (also known as Bai-Hua Qian Hu). Praeruptorin C is a calcium antagonist with pD2′ value of 5.7. Research Area：Cardiovascular Disease Targets：Calcium Channel Related Screening Libraries:Natural Product Library Plus;Bioactive […]

For research use only. We do not sell to patients. Relugolix-d6 Biological Activity：Relugolix-d6 is deuterium labeled Relugolix. Relugolix (TAK-385) is a potent, orally active, nonpeptidic gonadotropin-releasing hormone (GnRH) antagonist. Relugolix possesses high affinity and potent antagonistic activity for human receptor (binding IC50=0.33 nM) and monkey receptor (IC50=0.32 nM) compared with TAK-013 (HY-100209). Relugolix is used for […]

For research use only. We do not sell to patients. ML354 CAS No. : 89159-60-4 Biological Activity：ML354 is a selective PAR4 antagonist with an IC50 of 140 nM. Research Area：Others Targets：Protease Activated Receptor (PAR) Related Small Molecules:ENMD-1068 hydrochloride;Atopaxar hydrobromide;SLIGRL-NH2 TFA;SCH79797 dihydrochloride;AC-55541;TRAP-6-IN-1;TRAP-6 amide TFA;I-191;Parstatin(human);UDM-001651;AZ8838;Protease-Activated Receptor-1, PAR-1 Agonist;TFLLR-NH2(TFA);tcY-NH2;VKGILS-NH2 TFA;2-Furoyl-LIGRLO-amide TFA;Protease-Activated Receptor-1 antagonist 1;GB-110;Protease-Activated Receptor-1 antagonist 2;RWJ-56110 dihydrochloride;Trypsin;TRAP-6;Protease-Activated Receptor-3 (PAR-3) […]

For research use only. We do not sell to patients. Histamine H4 receptor antagonist-1 CAS No. : 1246207-84-0 Biological Activity：Histamine H4 receptor antagonist-1 is an antagonist of histamine H4 receptor extracted from patent WO2010108059A1 compound 60. Research Area：Inflammation/Immunology Targets：Histamine Receptor Related Small Molecules:Tripelennamine;Brompheniramine-d6 maleate;Samelisant;Chlorphenoxamine;H3 receptor-MO-1;Diphenhydramine;ABT-239;Ketotifen fumarate;Ranitidine;Cetirizine;Diphenylpyraline hydrochloride;Loratadine-d5;Phenyltoloxamine;Ritanserin;BMY-25271;FRG8701;Mecamylamine hydrochloride;Cimetidine sulfoxide;Brompheniramine maleate;Tecastemizole;Famotidine-13C,d3;Bromazine-d6 hydrochloride Trending products：Recombinant Proteins  |  […]

For research use only. We do not sell to patients. BIIL-260 hydrochloride CAS No. : 192581-24-1 Biological Activity：BIIL-260 hydrochloride is a potent and long-acting orally active leukotriene B(4) receptor LTB4 antagonist, with anti-inflammatory activity. BIIL-260 hydrochloride interacts with the LTB4 receptor in a saturable, reversible, and competitive manner, has high affinity to the LTB4 receptor […]