Tag: Antagonist

For research use only. We do not sell to patients. CB1 antagonist 1 CAS No. : 890037-68-0 Biological Activity：CB1 antagonist 1 is an antagonist of CB1 receptor, used in the research of metabolic syndrome and obesity, neuroinflammatory disorders, cognitive disorders and psychosis, gastrointestinal disorders, and cardiovascular conditions. Research Area：Metabolic Disease|Inflammation/Immunology|Neurological Disease|Cardiovascular Disease Targets：Cannabinoid Receptor Related […]

For research use only. We do not sell to patients. NPS ALX Compound 4a dihydrochloride CAS No. : 1781934-44-8 Biological Activity：NPS ALX Compound 4a dihydrochloride is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM. Research Area：Neurological Disease Targets：5-HT Receptor Related Small Molecules:F 13714;Mosapride-d5;Nuciferine;Renzapride;LY […]

For research use only. We do not sell to patients. [D-p-Cl-Phe6,Leu17]-VIP CAS No. : 102805-45-8 Biological Activity：[D-p-Cl-Phe6,Leu17]-VIP is a competitive and selective antagonist of vasoactive intestinal peptide (VIP) receptor, with the IC50 of 125.8 nM. [D-p-Cl-Phe6,Leu17]-VIP has no activity on glucagon, secretin or GRF receptors[2][3]. Research Area：Inflammation/Immunology|Neurological Disease Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole […]

For research use only. We do not sell to patients. NEP(1-40) CAS No. : 475221-20-6 Biological Activity：NEP(1-40) is a Nogo-66 receptor (NgR) antagonist peptide, reversing the injury-induced shift in distribution of microglia morphologies by limiting myelin-based inhibition. Research Area：Inflammation/Immunology Targets：Others Related Screening Libraries:Bioactive Compound Library Plus;Peptide Library; Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl […]

For research use only. We do not sell to patients. Lanicemine dihydrochloride CAS No. : 153322-06-6 Biological Activity：Lanicemine (AZD6765) dihydrochloride is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects. Research Area：Neurological Disease Targets：iGluR Related Screening Libraries:Drug Repurposing […]

For research use only. We do not sell to patients. Estrogen receptor antagonist 5 CAS No. : 2136600-69-4 Biological Activity：Estrogen receptor antagonist 5 is a potent antagonist of Estrogen receptor. The estrogen receptor is a ligand-activated transcriptional regulatory protein that mediates induction of a variety of biological effects through its interaction with endogenous estrogens. Estrogen […]

For research use only. We do not sell to patients. Naloxonazine dihydrochloride CAS No. : 880759-65-9 Biological Activity：Naloxonazine dihydrochloride is a specific μ-opioid receptor antagonist with an IC50 of 5.4 nM. Naloxonazine dihydrochloride also shows anti-leishmanial activity[2][3]. Research Area：Infection|Neurological Disease Targets：Opioid Receptor Related Small Molecules:ORL1 antagonist 1;Loperamide-d6 N-Oxide;Deltorphin 2 TFA;Nalfurafine;β-Lipotropin (60-65);GSK1521498 free base;Trimebutine-d5 fumarate;Dynorphin B […]

For research use only. We do not sell to patients. RD162 CAS No. : 915087-27-3 Biological Activity：RD162, a diarylthiohydantoin, is an orally active non-steroidal antiandrogen (NSAA). RD162 specifically binds to androgen receptor (AR). RD162 induces tumor regression in mouse models of castration-resistant human prostate cancer. Research Area：Cancer Targets：Androgen Receptor Related Small Molecules:VPC-14449;AC-262536;GTx-007;Linuron-d6;MI-136;VPC-13789;ARD-2585;PF-998425;GSK-2881078;PROTAC AR Degrader-4;RU 58841;Triptophenolide;ARD-61;Dehydroisoandrosterone […]

For research use only. We do not sell to patients. Ondansetron hydrochloride dihydrate CAS No. : 103639-04-9 Biological Activity：Ondansetron (GR 38032) hydrochloride dehydrate is an orally active, highly selective and competitive 5-HT3 receptor antagonist (crosses the blood-brain barrier). Ondansetron hydrochloride dehydrate can be used in studies of preventing nausea and vomiting associated with cancer chemotherapy, […]

For research use only. We do not sell to patients. I-191 CAS No. : 1690172-25-8 Biological Activity：I-191 is a potent, selective protease-activated receptor 2 (PAR2) antagonist. Research Area：Cancer Targets：Protease Activated Receptor (PAR) Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Anti-Cancer Compound Library;Targeted Diversity Library;Coagulation and Anti-coagulation Compound Library; Related Small Molecules:ENMD-1068 hydrochloride;Atopaxar hydrobromide;SLIGRL-NH2 TFA;SCH79797 […]