Tag: Antagonist

For research use only. We do not sell to patients. K34c CAS No. : 939769-93-4 Biological Activity：K34c is a potent and selective α5β1 integrin antagonist. K34c can be used for glioblastoma research. Research Area：Cancer Targets：Integrin Related Small Molecules:GRGDSPK;Integrin Binding Peptide;Cyclo(Arg-Gly-Asp-D-Phe-Cys);Zaurategrast ethyl ester sulfate;HSDVHK-NH2;Lifitegrast sodium;TC-I 15;α2β1 Integrin Ligand Peptide;Integrin modulator 1;Veltuzumab;GRGDSP TFA;Cyclo(-RGDfK) TFA;Zalunfiban;THI0019;RGD;Arg-Gly-Asp-Ser (TFA);BIRT 377;αvβ1 integrin-IN-1;RGD-4C;LXW7;Fradafiban;Firategrast;EILEVPST;Valategrast […]

For research use only. We do not sell to patients. Sonidegib CAS No. : 956697-53-3 Biological Activity：Sonidegib (Erismodegib) is a potent and selective Smo antagonist with IC50 of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively. Research Area：Cancer Targets：Smo Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved […]

For research use only. We do not sell to patients. SSTR5 antagonist 1 CAS No. : 1628741-91-2 Biological Activity：SSTR5 antagonist 1 (compound 25a) is a selective and orally available somatostatin receptor subtype 5 (SSTR5) antagonist with IC50s of 9.6 and 57 nM for hSSTR5 and mSSTR5, respectively. Research Area：Metabolic Disease|Endocrinology Targets：Somatostatin Receptor Related Screening Libraries:Bioactive […]

For research use only. We do not sell to patients. A1/A3 AR antagonist 1 Biological Activity：A1/A3 AR antagonist 1 (compound 10) is a potent adenosine 1 (A1) and adenosine 3 (A3) receptor dual antagonist with Kis of 36.7 nM, 25.4 nM and 1.47 nM for human A1, human A3 and rat A1, respectively. A1/A3 AR […]

For research use only. We do not sell to patients. Bepridil hydrochloride hydrate CAS No. : 74764-40-2 Biological Activity：Bepridil hydrochloride hydrate ((±)-Bepridil hydrochloride hydrate) is a non-selective, long-acting Ca+ channel antagonist and Na+, K+ channel inhibitor, with antianginal and type I antiarrhythmic effects. Bepridil hydrochloride hydrate also acts as a cardiac Na+/Ca2+ exchange (NCX1) inhibitor. […]

For research use only. We do not sell to patients. CFM-2 CAS No. : 178616-26-7 Biological Activity：CFM-2 is a potent and selective non-competitive AMPAR antagonist. CFM-2 possesses anticonvulsant activity in various models of seizures[2]. Research Area：Neurological Disease|Cancer Targets：iGluR Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling Compound Library;Anti-Cancer Compound Library;Neurotransmitter Receptor Compound […]

For research use only. We do not sell to patients. Phenoxybenzamine CAS No. : 59-96-1 Biological Activity：Phenoxybenzamine is a nonselective, irreversible, orally active α-adrenoceptor antagonist that is commonly used for the research of hypertension, specifically caused by pheochromocytoma. Phenoxybenzamine also shows antitumor activity[2]. Research Area：Cancer|Endocrinology|Cardiovascular Disease Targets：Adrenergic Receptor Related Small Molecules:Todralazine;ARC 239 dihydrochloride;Yohimbine;Glaucine;Salbutamol;BI-167107;Talibegron hydrochloride;Arotinolol;SR59230A;Higenamine hydrochloride;Navafenterol […]

For research use only. We do not sell to patients. Icatibant acetate CAS No. : 138614-30-9 Biological Activity：Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC50 and Ki of 1.07 nM and 0.798 nM respectively[2][3]. Research Area：Inflammation/Immunology Targets：Bradykinin Receptor Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved […]

For research use only. We do not sell to patients. TG6-10-1 CAS No. : 1415716-58-3 Biological Activity：TG6-10-1 is an EP2 antagonist, shows low-nanomolar antagonist activity against only EP2, >300-fold selectivity over human EP3, EP4, and IP receptors, 100-fold selectivity over EP1 receptors. Research Area：Neurological Disease|Endocrinology Targets：5-HT Receptor|Prostaglandin Receptor Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound […]

For research use only. We do not sell to patients. Anisotropine bromide CAS No. : 80-50-2 Biological Activity：Anisotropine (Octatropine) bromide is an orally active anticholinergic muscarinic antagonist. Anisotropine bromide can inhibit gastric acid secretion and is used as an adjunct to peptic ulcers. Research Area：Metabolic Disease|Neurological Disease Targets：mAChR Related Small Molecules:VU0357017 hydrochloride;TBPB;Imidafenacin;Sabcomeline;MK-6884;Brompheniramine-d6 maleate;Navafenterol saccharinate;DREADD agonist […]