Tag: Antagonist

For research use only. We do not sell to patients. Fevipiprant CAS No. : 872365-14-5 Biological Activity：Fevipiprant (QAW039, NVP-QAW039) is s an orally active, selective, reversible prostaglandin D2 (DP2) receptor antagonist with an Kd value of 1.14 nM. Fevipiprant has the potential for the research of bronchial asthma[2][3]. Research Area：Cardiovascular Disease Targets：Prostaglandin Receptor Related Screening […]

For research use only. We do not sell to patients. TAN-452 CAS No. : 892039-23-5 Biological Activity：TAN-452 is an orally active, selective peripherally acting δ-opioid receptor (DOR) antagonist with a Ki of 0.47 nM and a Kb of 0.21 nM. TAN-452 is an antagonist for μ-opioid receptor (MOR; Ki=36.56 nM and Kb=9.43 nM) and κ-opioid receptor (KOR; Ki=5.31 nM and […]

For research use only. We do not sell to patients. Eticlopride hydrochloride CAS No. : 97612-24-3 Biological Activity：Eticlopride hydrochloride, a selective dopamine D2‐like receptor antagonist, exhibits high affinity for dopamine D2, α1‐adrenergic, α2‐adrenergic, 5HT1, 5HT2 receptors with Kis of 0.09, 112, 699, 6220, and 830 nM, respectively. Antipsychotic agent. Research Area：Neurological Disease Targets：Dopamine Receptor Related […]

For research use only. We do not sell to patients. (S)-Mirtazapine CAS No. : 61337-87-9 Biological Activity：(S)-Mirtazapine ((S)-Org3770) is a S(+)-enantiomer of Mirtazapine with pronociceptive properties in an animal model of acute thermal nociception. (S)-Mirtazapine is a stereoselective 5-HT2 receptor antagonist. (S)-Mirtazapine is metabolized by CYP2D6 and CYP1A2. Research Area：Neurological Disease Targets：5-HT Receptor Related Screening […]

For research use only. We do not sell to patients. Orphenadrine-d3 citrate Biological Activity：Orphenadrine-d3 citrate is the deuterium labeled Orphenadrine citrate. Orphenadrine citrate is a NMDA receptor antagonist with Ki of 6.0 +/- 0.7 μM, HERG potassium channel blocker. Research Area：Neurological Disease Targets：iGluR Related Small Molecules:CIQ;Quinolinic acid-d3;1-Aminocyclobutanecarboxylic acid;Glycine-1-13C,15N;ZL006;PYD-106;NMDA-IN-2;JAMI1001A;(S)-Willardiine;Fanapanel;(S)-AMPA;L-Glutamic acid-15N,d5;PDZ1 Domain inhibitor peptide TFA;Ifenprodil tartrate;Rislenemdaz;Coluracetam;Flupirtine-d4 hydrochloride;DL-Phenylalanine-d5 […]

For research use only. We do not sell to patients. DL-Phenylalanine-d5 hydrochloride Biological Activity：DL-Phenylalanine-d5 (2-Amino-3-phenylpropionic acid-d5) hydrochloride is the deuterium labeled DL-Phenylalanine hydrochloride. L-Phenylalanine hydrochloride is an essential amino acid isolated from Escherichia coli. L-Phenylalanine hydrochloride is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine hydrochloride is a […]

For research use only. We do not sell to patients. SB-222200 CAS No. : 174635-69-9 Biological Activity：SB-222200 is a potent, selective, orally active and blood-brain barrier (BBB) penetrant NK-3 receptor antagonist. SB-222200 is developed for central nervous system (CNS) disorders. Research Area：Neurological Disease|Endocrinology Targets：Neurokinin Receptor Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling […]

For research use only. We do not sell to patients. 2-Methoxyidazoxan monohydrochloride CAS No. : 109544-45-8 Biological Activity：2-Methoxyidazoxan monohydrochloride (RX821002 hydrochloride) is a highly selective alpha 2-adrenoceptor antagonist with little or no imidazoline antagonist effect. RX 821002 has markedly higher affinity for (guinea-pig) alpha 2D-adrenoceptors (pKd 9.7) than for (rabbit) alpha 2A-adrenoceptors (pKd 8.2)[2]. Research […]

For research use only. We do not sell to patients. Spiramide CAS No. : 510-74-7 Biological Activity：Spiramide (AMI-193) is a potent and selective antagonist of 5-HT2 and dopamine D2 receptor, with Kis of 2 nM and 3 nM, respectively. Spiramide has >2000-fold selectivity for 5-HT2 versus 5-HT1C (Ki=4300 nM) receptors. Spiramide exhibits antipsychotic activity[2][3]. Research […]

For research use only. We do not sell to patients. RF9 hydrochloride Biological Activity：RF9 hydrochloride is a potent and selective Neuropeptide FF receptor antagonist, with Ki values of 58 and 75 nM for hNPFF1R and hNPFF2R, respectively[2]. Research Area：Endocrinology|Neurological Disease|Cardiovascular Disease Targets：Neuropeptide Y Receptor Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound […]