Tag: Antagonist

For research use only. We do not sell to patients. JW74 CAS No. : 863405-60-1 Biological Activity：JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling with an IC50 of 420 nM. Research Area：Cancer Targets：Wnt Related Screening Libraries:Bioactive Compound Library Plus;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Cytoskeleton Compound Library;Neuroprotective Compound Library;Anti-Breast Cancer […]

For research use only. We do not sell to patients. PMX 205 CAS No. : 514814-49-4 Biological Activity：PMX 205 is a potent complement C5a receptor (C5aR; CD88) antagonist. Research Area：Inflammation/Immunology Targets：Complement System Related Small Molecules:Cemdisiran;Pelecopan;EG00229;Factor B-IN-2;Tesidolumab;Factor B-IN-3;Avacincaptad pegol;Sutimlimab;FD-IN-1;NDT 9513727;Cyclosporin A;AMY-101;Lipoteichoic acid;Iptacopan;Entadamide-A-β-D-glucopyranoside;Compstatin TFA;C5aR-IN-2;BCX 1470;EG01377;TLQP-21;W-54011;Complement C5-IN-1;PMX-53;(Z)-Leukadherin-1 Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  […]

For research use only. We do not sell to patients. Methapyrilene hydrochloride CAS No. : 135-23-9 Biological Activity：Methapyrilene (Thenylpyramine) hydrochloride is an orally active H1-receptor antihistamine and an anticholinergic agent of the pyridine chemical class. Methapyrilene hydrochloride has hepatotoxicity and can be used as a hepatotoxin that cause periportal hepatic necrosis in vivo[2] Research Area：Inflammation/Immunology […]

For research use only. We do not sell to patients. Asenapine maleate CAS No. : 85650-56-2 Biological Activity：Asenapine maleate is a 5-HT (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) and D2 antagonist with Ki values of 0.03-4.0 nM, 1.3nM, respectively, and an antipsychotic. Research Area：Neurological Disease Targets：5-HT Receptor Related Screening Libraries:Drug Repurposing Compound Library […]

For research use only. We do not sell to patients. Nizatidine-d3 CAS No. : 1246833-99-7 Biological Activity：Nizatidine-d3 is the deuterium labeled Nizatidine. Nizatidine is a potent and orally active histamine H2 receptor antagonist, can be used for the research of stomach and intestines ulcers. Nizatidine works by decreasing the secretion of gastric acid the stomach makes and prevent […]

For research use only. We do not sell to patients. CCR6 antagonist 1 CAS No. : 588674-64-0 Biological Activity：CCR6 antagonist 1 is a CCR6 antagonist that inhibits the CCL20/CCR6 axis. CCR6 antagonist 1 can be used in the research of autoimmune-mediated inflammatory diseases, such as inflammatory bowel diseases (IBDs). Research Area：Inflammation/Immunology Targets：CCR Related Small Molecules:LMD-009;PF-04634817 […]

For research use only. We do not sell to patients. Homatropine CAS No. : 87-00-3 Biological Activity：Homatropine is an orally active muscarinic acetylcholine receptor antagonist and can be used as an anticholinergic agent. Research Area：Neurological Disease Targets：mAChR Related Small Molecules:VU0357017 hydrochloride;TBPB;Imidafenacin;Sabcomeline;MK-6884;Brompheniramine-d6 maleate;Navafenterol saccharinate;DREADD agonist 21;Cyclobuxine D;Brompheniramine maleate;Dexetimide;Anisodamine hydrobromide;Anisotropine bromide;PD 102807;Nebracetam hydrochloride;Muscarine-d9 iodide;Mazaticol;VU0455691;Arborine;Oxitropium Bromide;Propiverine hydrochloride;VU0152099;MHP 133;YM-58790;Elucaine;Rispenzepine;Phenglutarimid;Rapacuronium […]

For research use only. We do not sell to patients. Orvepitant maleate CAS No. : 579475-24-4 Biological Activity：Orvepitant maleate (GW823296 maleate) is potent, selective, orally active and well-tolerated neurokinin-1 receptor (NK-1) antagonist with a pKi of 10.2 for human neurokinin-1 receptor. Orvepitant maleate can across the blood-brain barrier. Orvepitant maleate has the potential for depressive […]

For research use only. We do not sell to patients. EG00229 CAS No. : 1210945-69-9 Biological Activity：EG00229 is a neuropilin 1 (NRP1) receptor antagonist. EG00229 selectively inhibits VEGF-A binding to NRP1 b1 domain with an IC50 of 3 μM, but has no effect on VEGFA binding to VEGFR-1 and VEGFR-2. Research Area：Cancer Targets：Complement System Related […]

For research use only. We do not sell to patients. Epinastine CAS No. : 80012-43-7 Biological Activity：Epinastine (WAL801) is an antihistamine and mast cell stabilizer. Epinastine is a potent, selective and orally-active histamine H1 receptor antagonist. Epinastine also inhibits IL-8 release and has an antiallergic action[2][3][4]. Research Area：Inflammation/Immunology|Endocrinology Targets：Histamine Receptor Related Screening Libraries:Drug Repurposing Compound […]