Tag: Antagonist

For research use only. We do not sell to patients. (1R,3S-)Solifenacin-d5 hydrochloride CAS No. : 1217810-85-9 Biological Activity：(1R,3S-)Solifenacin-d5 hydrochloride is the deuterium labeled Solifenacin D5 hydrochloride. Solifenacin D5 hydrochloride is a deuterium labeled Solifenacin hydrochloride. Solifenacin hydrochloride is a muscarinic receptor antagonist with pKis of 7.6, 6.9 and 8.0 for M1, M2 and M3 receptors, […]

For research use only. We do not sell to patients. RORγt Inverse agonist 8 CAS No. : 2079892-79-6 Biological Activity：RORγt Inverse agonist 8 is a potent, selective, orally bioavailable RORγt inverse agonist, with an IC50 of 19 nM for human RORγt-LBD. Research Area：Inflammation/Immunology Targets：ROR Related Small Molecules:RORγt inhibitor 1;GNE-6468;SR3335;RORγt inverse agonist 30;GNE-0946;RORγt inverse agonist 13;Vimirogant […]

For research use only. We do not sell to patients. AE0047 Hydrochloride CAS No. : 116308-56-6 Biological Activity：AE0047 Hydrochloride is a calcium blocker, used in the research of hypertensive disease. Research Area：Cardiovascular Disease Targets：Calcium Channel Related Small Molecules:Benidipine hydrochloride;CaV1.3 antagonist-1;14-Deoxyandrographolide;(Rac)-MEM 1003;Glaucine;Efonidipine hydrochloride monoethanolate;L-Ascorbic acid sodium salt;Brompheniramine-d6 maleate;MRS 1523;Nilvadipine;Lercanidipine;CP-060;Anipamil-d25 hydrochloride;ISX-9;ω-Conotoxin MVIIC;Catharanthine;Thapsigargin;Tetrandrine;Ginsenoside Rd;Manidipine dihydrochloride;ω-Agatoxin IVA;PDE1-IN-4 Trending products：Recombinant […]

For research use only. We do not sell to patients. CP-96486 CAS No. : 139401-45-9 Biological Activity：CP-96486 is a potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonist with Kis of 20 and 24 nM, respectively. Research Area：Inflammation/Immunology Targets：Leukotriene Receptor Related Small Molecules:Pranlukast-d4;Verlukast-d6;Ablukast;MK-886;BIIL-260 hydrochloride;Pranlukast;γ-Linolenic acid ethyl ester;REV 5901;U-75302;RS-601;Tipelukast;LM-1484;RG-12525;Quinotolast sodium;Darbufelone mesylate;Chamazulene;11-​Keto-​beta-​boswellic acid;AS-35;Fiboflapon;BAY-u 9773;ONO4057;CP-96021 […]

For research use only. We do not sell to patients. A55453 CAS No. : 89687-06-9 Biological Activity：A55453 is a prazosin analogue and a potent α1-adrenergic antagonist. 125I-A55453 is a high-affinity alpha 1-adrenergic receptor probe. Research Area：Others Targets：Adrenergic Receptor Related Small Molecules:Todralazine;ARC 239 dihydrochloride;Yohimbine;Glaucine;Salbutamol;BI-167107;Talibegron hydrochloride;Arotinolol;SR59230A;Higenamine hydrochloride;Navafenterol saccharinate;Isoprenaline hydrochloride;Bevantolol;Zilpaterol-d7;Ritanserin;Povafonidine;β3-AR agonist 1;Tulobuterol;AGN 192836;KUC-7322;Oxyfedrine;Urapidil hydrochloride;Detomidine hydrochloride;Oxprenolol-d7 hydrochloride;Nicergoline;Synephrine hemitartrate;ADRA1D receptor […]

For research use only. We do not sell to patients. mGluR2 antagonist 1 CAS No. : 1432728-49-8 Biological Activity：mGluR2 antagonist 1 is a highly potent, orally bioavailable and selective class of mGluR2 negative allosteric modulator (IC50 of 9 nM) with excellent brain permeability. Research Area：Neurological Disease Targets：mGluR Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound […]

For research use only. We do not sell to patients. Cimetidine sulfoxide CAS No. : 54237-72-8 Biological Activity：Cimetidine sulfoxide (Cimetidine sulphoxide) is a sulfoxide metabolite of Cimetidine. Cimetidine is a histamine H2-receptor antagonist. Cimetidine has the potential for peptic ulcer disease and upper gastrointestinal haemorrhage treatment. Research Area：Inflammation/Immunology Targets：Histamine Receptor Related Screening Libraries:Bioactive Compound Library […]

For research use only. We do not sell to patients. SB-657510 CAS No. : 474960-44-6 Biological Activity：SB-657510 is a selective urotensin II (UII) receptor (UT) antagonist. The Ki values are 61, 17, 30, 65 and 56 nM for human, monkey, cat, rat and mouse receptors, respectively. SB-657510 exerts anti-inflammatory effects by inhibiting UII-induced upregulation of […]

For research use only. We do not sell to patients. ODN 2088 CAS No. : 1146541-45-8 Biological Activity：ODN 2088 is a potent TLR3, TLR7 and TLR9 inhibitor. ODN 2088 shows no cytotoxic. ODN 2088 inhibits the release of IFN-α and IL-6[2][3]. Research Area：Inflammation/Immunology Targets：Toll-like Receptor (TLR) Related Screening Libraries:Bioactive Compound Library Plus; Related Small Molecules:C29;TMX-201;RS […]

For research use only. We do not sell to patients. H-151 CAS No. : 941987-60-6 Biological Activity：H-151 is a potent, selective and covalent antagonist of STING that has noteworthy inhibitory activity both in cells and in vivo. H-151 reduces TBK1 phosphorylation and suppresses STING palmitoylation. H-151 can be used for the research of autoinflammatory disease. […]