Tag: Antagonist

For research use only. We do not sell to patients. D4R antagonist-1 Biological Activity：D4R antagonist-1 is a potent and selective D4R antagonist with an IC50 of 6.87 µM. D4R antagonist-1 has the potential for the research of Parkinson’s disease. Research Area：Neurological Disease Targets：Dopamine Receptor Related Small Molecules:Alizapride hydrochloride;Thioproperazine;Bromopride-d3;Nuciferine;Glaucine;SB-277011 dihydrochloride;MIF-1 TFA;Sulpiride;(Rac)-Razpipadon;Clebopride malate;WAY-100635;Flupentixol-d4 dihydrochloride;Cariprazine-d6 hydrochloride;Itopride-d6 hydrochloride;ONC206;Brexpiprazole S-oxide;cis-(Z)-Flupentixol […]

For research use only. We do not sell to patients. DS08210767 CAS No. : 2376334-75-5 Biological Activity：DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM. Research Area：Metabolic Disease|Endocrinology Targets：Thyroid Hormone Receptor Related Screening Libraries:Bioactive Compound Library Plus; Related Small Molecules:(D-Trp12,Tyr34)-pTH (7-34) amide (bovine);L-Thyroxine sodium;TR antagonist 1;TRβ agonist 1;1α-Hydroxy-3-epi-vitamin D3;Thyroxine sulfate;Thyroxine […]

For research use only. We do not sell to patients. 2-Methylthio-AMP diTEA CAS No. : 1227193-98-7 Biological Activity：2-Methylthio-AMP (2-MeSAMP) diTEA is a selective and direct P2Y12 antagonist. 2-Methylthio-AMP diTEA is an inhibitor of ADP-dependent platelet aggregation[2][3]. Research Area：Cardiovascular Disease Targets：P2Y Receptor Related Small Molecules:YM-254890;BPTU;Uridine 5′-diphosphoglucose disodium salt;AZD1283;Antiplatelet agent 1;NF546;MRS2395;PSB-1114 tetrasodium;Vicagrel;Cangrelor tetrasodium;MRS2179 tetrasodium hydrate;PSB-0739;PIT;MRS2279;MRS2768 tetrasodium salt;PPTN […]

For research use only. We do not sell to patients. Nastorazepide CAS No. : 209219-38-5 Biological Activity：Nastorazepide (Z-360) is a selective, orally available, 1,5-benzodiazepine-derivative gastrin/cholecystokinin 2 (CCK-2) receptor antagonist with potential antineoplastic activity. Target：CCK-2 in vitro: Z-360 binds to the gastrin/CCK-2 receptor, thereby preventing receptor activation by gastrin, a peptide hormone frequently associated with the […]

For research use only. We do not sell to patients. (D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P CAS No. : 84676-91-5 Biological Activity：(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P is a neuropeptide Substance P (HY-P0201) antagonist. Research Area：Neurological Disease Targets：Neurokinin Receptor Related Small Molecules:(β-Ala8)-Neurokinin A (4-10);Talnetant hydrochloride;Pavinetant;MEN11467;Vapreotide acetate;Rolapitant;Eprazinone dihydrochloride;Orvepitant maleate;Netupitant metabolite Monohydroxy Netupitant;SB-222200;Senktide;GR 87389;Hemokinin 1, human;Neurokinin A TFA;Imnopitant dihydrochloride;[Glp6] Substance P (6-11);[Lys5,MeLeu9,Nle10]-NKA(4-10) TFA;[Pro9]-Substance P;Befetupitant;Hemokinin 1 […]

For research use only. We do not sell to patients. IL-17A antagonist 1 CAS No. : 2205034-18-8 Biological Activity：IL-17A antagonist 1 (compound 1) is an IL-17A antagonist, with a Kd of 0.66 μM and an IC50 of 1.14 μM. Research Area：Inflammation/Immunology Targets：Interleukin Related Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Angiogenesis-Related Compound Library;Antidepressant Compound Library; […]

For research use only. We do not sell to patients. Asoxime dichloride CAS No. : 34433-31-3 Biological Activity：Asoxime dichloride (HI-6) is an antagonist to acetylcholine receptors (AChRs) including the nicotinic receptor, α7 nAChR. Asoxime dichloride involves in modulating immunity response. Asoxime dichloride (HI-6) can be used as an antigen and improves vaccination efficacy in the […]

For research use only. We do not sell to patients. JTC-801 CAS No. : 244218-51-7 Biological Activity：JTC-801 is a selective opioid receptor-like1 (ORL1) receptor antagonist, binding to ORL1 receptor with a Ki value of 8.2 nM. Research Area：Neurological Disease Targets：Opioid Receptor Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;Neurotransmitter Receptor Compound Library;Anti-Obesity […]

For research use only. We do not sell to patients. ROR agonist-1 CAS No. : 2361528-74-5 Biological Activity：ROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), inhibition of IL-17A production from human primary TH 17 cells with a pIC50 of 7.5. Research Area：Inflammation/Immunology Targets：ROR Related […]

For research use only. We do not sell to patients. N-0861 racemate CAS No. : 121241-87-0 Biological Activity：N-0861 racemate is the racemate of N-0861. N-0861 is a selective adenosine A1 receptor antagonist. Research Area：Cardiovascular Disease Targets：Adenosine Receptor Related Small Molecules:MRS 1523;APNEA;MIPS521;Derenofylline;FSCPX;Theobromine-d3;Inosine-13C;Norisoboldine;Xanthine amine congener dihydrochloride;LUF6096;A1/A3 AR antagonist 1;ATL-801;Istradefylline;Doxofylline-d6;A1AR antagonist 3;MRS1186;A2A/A3 AR antagonist-1;A2AAR/HDAC-IN-2;MRS-1191;MRS5698;GP531;Imaradenant;PSB-0788 Trending products：Recombinant Proteins  |  Bioactive […]