Tag: Antagonist

For research use only. We do not sell to patients. HSDVHK-NH2 CAS No. : 848644-86-0 Biological Activity：HSDVHK-NH2 is an antagonist of the integrin αvβ3-vitronectin interaction, with an IC50 of 1.74 pg/mL (2.414 pM)[2]. Research Area：Cancer Targets：Integrin Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Anti-Cancer Compound Library;Cytoskeleton Compound Library;Targeted Diversity Library;Peptide Library;Coagulation and Anti-coagulation Compound Library; […]

For research use only. We do not sell to patients. AF-353 CAS No. : 865305-30-2 Biological Activity：AF-353 (Ro-4) is a potent, selective and orally bioavailable P2X3/P2X2/3 receptor antagonist, with a pIC50 of 8.0 for both human and rat P2X3, and with a pIC50 of 7.3 for human P2X2/3[2]. Research Area：Cancer Targets：P2X Receptor Related Screening Libraries:Bioactive […]

For research use only. We do not sell to patients. JNJ-5207787 CAS No. : 683746-68-1 Biological Activity：JNJ-5207787 is a nonpeptidic, selective and penetrate the blood-brain barrier neuropeptide Y Y2 receptor (Y2) antagonist. JNJ-5207787 inhibits the binding of peptide YY (PYY) with pIC50s of 7.0 and 7.1 for human Y2 receptor and rat Y2 receptor, respectively. […]

For research use only. We do not sell to patients. Ononetin CAS No. : 487-49-0 Biological Activity：Ononetin, a natural deoxybenzoin, is a potent and selective TRPM3 channel blocker with an IC50 of 0.3 μM. Research Area：Neurological Disease Targets：TRP Channel Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling Compound Library;Natural […]

For research use only. We do not sell to patients. Bevurogant CAS No. : 1817773-66-2 Biological Activity：Bevurogant is a retinoid-related orphan receptor-gamma t (RORγt) antagonist. Bevurogant can be used for the research of chronic inflammatory diseases. Research Area：Inflammation/Immunology Targets：ROR Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Small Molecule Immuno-Oncology Compound Library;Transcription Factor-Targeted Library;Nuclear […]

For research use only. We do not sell to patients. Handle region peptide, rat CAS No. : 749227-53-0 Biological Activity：Handle region peptide, rat is a prorenin receptor antagonist, suppresses the progression of diabetic nephropathy and has anti-inflammatory in the eye. Research Area：Inflammation/Immunology Targets：Renin Related Small Molecules:Remikiren;Renin inhibitor-1;SPH3127;Araloside A;Enalkiren;VTP-27999 TFA;Lyciumin A;ACT 178882;Renin substrate 1 Trending products：Recombinant […]

For research use only. We do not sell to patients. Gabazine CAS No. : 104104-50-9 Biological Activity：Gabazine is a selective and competitive antagonist of GABAA receptor, with an IC50 of ~0.2 μM for GABA receptor. Research Area：Neurological Disease Targets：GABA Receptor Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling Compound Library;Neurotransmitter Receptor Compound […]

For research use only. We do not sell to patients. Vercirnon CAS No. : 698394-73-9 Biological Activity：Vercirnon (GSK1605786A) is an orally bioavailable, selective, and potent antagonist of CCR9. Vercirnon inhibits CCR9-mediated Ca2+ mobilization and chemotaxis on Molt-4 cells with IC50 values of 5.4 and 3.4 nM, respectively. Vercirnon is selective for CCR9 over CCR1-12 and […]

For research use only. We do not sell to patients. Pexopiprant CAS No. : 932708-14-0 Biological Activity：Pexopiprant is an oral antagonist of the prostaglandin D2 receptor 2 (DP2),Ki ＜ 100nM. Pexopiprant can be used in studies of asthma. Research Area：Others Targets：Prostaglandin Receptor Related Screening Libraries:Bioactive Compound Library Plus; Related Small Molecules:Omidenepag isopropyl;DG-041;8-Isoprostaglandin E2;BAY-6672;trans-Isoferulic acid;GSK-269984A;KMN-80;SC 51089;p-Hydroxycinnamic […]

For research use only. We do not sell to patients. EMD 66684 CAS No. : 1216884-39-7 Biological Activity：EMD 66684 is an antagonist of Angiotensin II Type 1 (AT1) receptor. EMD 66684 shows potent binding affinities for the AT1 subtype Ang II receptor with an IC50 value of 0.7 nM. EMD 66684 also serves as an […]