Tag: Antagonist

For research use only. We do not sell to patients. Clothiapine CAS No. : 2058-52-8 Biological Activity：Clothiapine, an atypical antipsychotic agent, shares with clozapine its strong antiserotonergic properties. Research Area：Neurological Disease Targets：5-HT Receptor Related Small Molecules:F 13714;Mosapride-d5;Nuciferine;Renzapride;LY 344864 racemate;Harmine hydrochloride;Valerenic acid;Arotinolol;Melitracen-d6 hydrochloride;WAY-100635;Nelotanserin;Flupentixol-d4 dihydrochloride;Cariprazine-d6 hydrochloride;Tetrahydro-β-carboline;CP-809101;Volinanserin-d4 hydrochloride;Masupirdine free base;BRL-15572 dihydrochloride;LY393558;Brexpiprazole S-oxide Trending products：Recombinant Proteins  |  Bioactive Screening […]

For research use only. We do not sell to patients. CXCR2 antagonist 4 Biological Activity：CXCR2 antagonist 4 (compound 7) is a potent CXCR2 antagonist with an IC50 value of 0.13 μM. CXCR2 antagonist 4 can inhibit CXCL8-induced cytosolic calcium increase (IC50 = 27 μM). CXCR2 antagonist 4 can be used for researching anticancer. Research Area：Cancer […]

For research use only. We do not sell to patients. JNJ-54717793 CAS No. : 1628843-99-1 Biological Activity：JNJ-54717793, as a brain penetrant, is an orally active, selective and high affinity orexin-1 receptor (OX1R) antagonist (plasma EC50=85 ng/mL). The Ki values of JNJ-54717793 for hOX1R (human OX1R) and hOX2R are 16 nM and 700 nM, respectively. JNJ-54717793 […]

For research use only. We do not sell to patients. GPR84 antagonist 3 Biological Activity：GPR84 antagonist 3 (compound 42) is a potent GPR84 (G-protein-coupled receptor 84) antagonist. GPR84 antagonist 3 inhibits GTPγS, with a pIC50 of 8.28. GPR84 antagonist 3 has a favorable pharmacokinetic profile suitable. Research Area：Inflammation/Immunology Targets：GPR84 Related Small Molecules:GLPG1205;6-OAU;GPR84 antagonist 2;GPR84 antagonist […]

For research use only. We do not sell to patients. [Des-His1,Glu9] Glucagon CAS No. : 110121-11-4 Biological Activity：[Des-His1,Glu9] Glucagon is a potent glucagon receptor system peptide antagonist. [Des-His1,Glu9] Glucagon enhances the glucose-stimulated release of insulin from pancreatic islet cells. [Des-His1,Glu9] Glucagon can be used to research diabetes. Research Area：Metabolic Disease Targets：GCGR Related Small Molecules:BETP;GLP-1R agonist […]

For research use only. We do not sell to patients. Cerlapirdine CAS No. : 925448-93-7 Biological Activity：Cerlapirdine (SAM-531, PF-05212365) is a selective and potent full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine has the potential for researching the Alzheimer’s disease. Research Area：Neurological Disease Targets：5-HT Receptor Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library […]

For research use only. We do not sell to patients. Lin28-let-7a antagonist 1 CAS No. : 2024548-03-4 Biological Activity：Lin28-let-7a antagonist 1 shows a clear antagonistic effect against the Lin28-let-7a interaction with an IC50 of 4.03 μM for Lin28A-let-7a-1 interaction. Research Area：Cancer Targets：MicroRNA Related Screening Libraries:Bioactive Compound Library Plus;Epigenetics Compound Library;Anti-Cancer Compound Library;Transcription Factor-Targeted Library; Related […]

For research use only. We do not sell to patients. Puerarin CAS No. : 3681-99-0 Biological Activity：Puerarin, an isoflavone extracted from Radix puerariae, is a 5-HT2C receptor antagonist. Research Area：Inflammation/Immunology|Cancer Targets：5-HT Receptor Related Screening Libraries:Natural Product Library Plus;Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound […]

For research use only. We do not sell to patients. Bevantolol CAS No. : 59170-23-9 Biological Activity：Bevantolol is a selective β-1 adrenoceptor antagonist. Bevantolol can be used for the research of angina pectoris and hypertension. Research Area：Cardiovascular Disease Targets：Adrenergic Receptor Related Small Molecules:Todralazine;ARC 239 dihydrochloride;Yohimbine;Glaucine;Salbutamol;BI-167107;Talibegron hydrochloride;Arotinolol;SR59230A;Higenamine hydrochloride;Navafenterol saccharinate;Isoprenaline hydrochloride;Zilpaterol-d7;Ritanserin;A55453;Povafonidine;β3-AR agonist 1;Tulobuterol;AGN 192836;KUC-7322;Oxyfedrine;Urapidil hydrochloride;Detomidine hydrochloride;Oxprenolol-d7 hydrochloride;Nicergoline;Synephrine […]

For research use only. We do not sell to patients. Dihydro-β-erythroidine CAS No. : 23255-54-1 Biological Activity：Dihydro-β-erythroidine is a a competitive nicotinic receptor antagonist. Dihydro-β-erythroidine blocks the discriminative stimulus properties of nicotine. Dihydro-β-erythroidine inhibits the anxiolytic effect of nicotine induced[2]. Research Area：Neurological Disease Targets：nAChR Related Small Molecules:Spinosad;Pyrantel;NS 9283;Myosmine-d4;Benzethonium chloride;A-867744;Catestatin;Asoxime dichloride;α7 nAchR-JAK2-STAT3 agonist 1;AR-R17779 hydrochloride;Mecamylamine hydrochloride;Tropisetron;Zolunicant;S16961;NS3861;(±)-Anatoxin […]