Tag: Antagonist

For research use only. We do not sell to patients. Ciproxifan maleate CAS No. : 184025-19-2 Biological Activity：Ciproxifan maleate (FUB 359 maleate) is a potent, selective, orally bioavailable and competitive antagonist of histamine H3-receptor, with an IC50 of 9.2 nM. Ciproxifan maleate displays low apparent affinity at other receptor subtypes. Ciproxifan maleate can be used […]

For research use only. We do not sell to patients. Asivatrep CAS No. : 1005168-10-4 Biological Activity：Asivatrep (PAC-14028) is a potent and selective transient receptor potential vanilloid type I (TRPV1) antagonist. Research Area：Inflammation/Immunology Targets：TRP Channel Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus; Related Small Molecules:V116517;GSK2332255B;Pregnenolone monosulfate sodium;TRPC5-IN-4;OptoBI-1;SB-705498;TRPC3/6-IN-1;ABT-239;Pyr3;Ononetin;TRPM8 antagonist 3;FEMA […]

For research use only. We do not sell to patients. Alosetron D3 Hydrochloride CAS No. : 1189919-71-8 Biological Activity：Alosetron D3 Hydrochloride (GR-68755C D3) is deuterium labeled Alosetron, which is a serotonin 5HT3-receptor antagonist. Research Area：Neurological Disease Targets：5-HT Receptor Related Small Molecules:F 13714;Mosapride-d5;Nuciferine;Renzapride;LY 344864 racemate;Harmine hydrochloride;Valerenic acid;Arotinolol;Melitracen-d6 hydrochloride;WAY-100635;Nelotanserin;Flupentixol-d4 dihydrochloride;Cariprazine-d6 hydrochloride;Tetrahydro-β-carboline;CP-809101;Volinanserin-d4 hydrochloride;Masupirdine free base;BRL-15572 dihydrochloride;LY393558;Brexpiprazole S-oxide Trending […]

For research use only. We do not sell to patients. Mesoridazine benzenesulfonate CAS No. : 32672-69-8 Biological Activity：Mesoridazine (TPS-23) benzenesulfonate, a metabolite of Thioridazine (HY-B0965A), acts as an orally active phenothiazine antipsychotic agent. Mesoridazine benzenesulfonate is a potent and rapid open-channel blocker of human ether-a-go-go related gene (hERG) channels and blocks hERG currents with an IC50 […]

For research use only. We do not sell to patients. Doxazosin D8 CAS No. : 1126848-44-9 Biological Activity：Doxazosin D8 (UK 33274 D8) is a deuterium labeled Doxazosin (UK 33274). Doxazosin is a quinazoline-derivative that selectively antagonizes postsynaptic α1 adrenergic receptors. Research Area：Endocrinology|Cardiovascular Disease Targets：Adrenergic Receptor Related Small Molecules:Todralazine;ARC 239 dihydrochloride;Yohimbine;Glaucine;Salbutamol;BI-167107;Talibegron hydrochloride;Arotinolol;SR59230A;Higenamine hydrochloride;Navafenterol saccharinate;Isoprenaline hydrochloride;Bevantolol;Zilpaterol-d7;Ritanserin;A55453;Povafonidine;β3-AR agonist […]

For research use only. We do not sell to patients. S1P2 antagonist 1 CAS No. : 2262402-83-3 Biological Activity：S1P2 antagonist 1 is an orally bioavailable S1P2 antagonist against fibrotic diseases. Research Area：Others Targets：LPL Receptor Related Small Molecules:GSK2018682;Ozanimod hydrochloride;BMS-986020 sodium;S1p receptor agonist 2;ONO-9780307;Siponimod hemifumarate;S1P1 agonist III;Ceralifimod;Ki16425;H2L 5765834;S1PR1 agonist 2;RP101442;S1PR1 agonist 1;CS-2100;ASP1126;1-Oleoyl lysophosphatidic acid;Ex26;RP-001 hydrochloride;VPC 23019;CYM-5541;LPA1 receptor […]

For research use only. We do not sell to patients. TLR7/8 antagonist 1 Biological Activity：TLR7/8 Antagonist 1 (Compound 16c) is the potent antagonist of TLR7/8 with IC50s of 3.91 and 2.19 μM, respectively. TLR7/8 Antagonist 1 is an imidazoquinoline derivative compound. Toll-like receptors (TLRs) 7 and 8 are key targets in the development of immunomodulatory […]

For research use only. We do not sell to patients. Masupirdine free base CAS No. : 701205-60-9 Biological Activity：Masupirdine free base (SUVN-502 free base) is a potent, selective, orally bioavailable, and brain penetrant 5-HT6 receptor antagonist (Ki of 2.04 nM for human 5-HT6 receptor). Masupirdine free base (SUVN-502 free base) shows high selectivity over 5-HT2A […]

For research use only. We do not sell to patients. BRL-15572 dihydrochloride CAS No. : 193611-72-2 Biological Activity：BRL-15572 dihydrochloride is a selective antagonist of h5-HT1D, displays high affinity for h5-HT1D receptors. BRL-15572 dihydrochloride could be useful pharmacological agents to characterise 5-HT1D receptor mediated responses. Research Area：Neurological Disease Targets：5-HT Receptor Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G […]

For research use only. We do not sell to patients. (R)-Bicalutamide-d4 CAS No. : 1217826-87-3 Biological Activity：(R)-Bicalutamide-d4 is the deuterium labeled (R)-Bicalutamide. (R)-Bicalutamide is the (R)-enantiomer of Bicalutamide (HY-14249). (R)-Bicalutamide is an androgen receptor (AR) antagonist, with antineoplastic activity. (R)-Bicalutamide is widely used for the research of prostate cancer[2]. Research Area：Cancer Targets：Androgen Receptor Related Small […]