Tag: Activator|Inhibitor

For research use only. We do not sell to patients. NBDHEX CAS No. : 787634-60-0 Biological Activity：NBDHEX is a potent glutathione S-transferase P1-1 (GSTP1-1) inhibitor. NBDHEX induces apoptosis of tumor cells. NBDHEX acts as an anticancer agent by inhibiting GSTs catalytic activity, avoiding inconvenience of the inhibitor extrusion from the cell by specific pumps and […]

For research use only. We do not sell to patients. K145 CAS No. : 1309444-75-4 Biological Activity：K145 is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 µM and a Ki of 6.4 µM. K145 is inactive against SphK1 and other protein kinases. K145 induces cell apoptosis and has potently antitumor […]

For research use only. We do not sell to patients. Niraparib hydrochloride CAS No. : 1038915-64-8 Biological Activity：Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib hydrochloride leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor […]

For research use only. We do not sell to patients. Articaine hydrochloride CAS No. : 23964-57-0 Biological Activity：Articaine hydrochloride (Hoe-045) is an amide anaesthetic containing an ester group, reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, can provide effective pain relief. Articaine hydrochloride ameliorates LPS-induced acute […]

For research use only. We do not sell to patients. Phenformin-d5 hydrochloride Biological Activity：Phenformin-d5 (Phenethylbiguanide-d5) hydrochloride is the deuterium labeled Phenformin hydrochloride. Phenformin hydrochloride is an anti-diabetic drug from the biguanide class, can activate AMPK activity[1][2]. Research Area：Cancer Targets：Autophagy|AMPK Related Small Molecules:AMPK activator 4;ZLN024;YLF-466D;BAY-3827;3α-Hydroxymogrol;HTH-01-015;TMPA;AICAR;Cimiracemoside C;HL271;EB-3D;COH-SR4;AMPK activator 7;Narazaciclib;D942;MARK4 inhibitor 1;Kazinol U;Phenformin hydrochloride;Karanjin;GSK621;Dorsomorphin;Palmitelaidic Acid;PF-06685249;Flufenamic acid-d4;PF-06679142 Trending products：Recombinant […]

For research use only. We do not sell to patients. TH1834 CAS No. : 2108830-08-4 Biological Activity：TH1834 is a specific Tip60 (KAT5) histone acetyltransferase (HAT) inhibitor. TH1834 induces apoptosis and increases DNA damage in breast cancer. TH1834 does not affect the activity of related histone acetyltransferase MOF. Anticancer activity. Research Area：Cancer Targets：Apoptosis|Histone Acetyltransferase Related Screening […]

For research use only. We do not sell to patients. AZD1208 CAS No. : 1204144-28-4 Biological Activity：AZD1208 is an orally bioavailable, highly selective PIM kinases inhibitor. Research Area：Cancer Targets：Autophagy|Pim|Apoptosis Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Epigenetics Compound Library;Immunology/Inflammation Compound Library;JAK/STAT Compound Library;Kinase Inhibitor Library;Anti-Cancer Compound Library;Clinical Compound Library;Autophagy Compound Library;Orally Active […]

For research use only. We do not sell to patients. PQ401 CAS No. : 196868-63-0 Biological Activity：PQ401 is a potent inhibitor of IGF-IR signaling. PQ401 inhibits IGF-I-stimulated IGF-IR autophosphorylation with an IC50 of 12.0 μM in a series of studies in MCF-7 cells. PQ401 is effective at inhibiting IGF-I-stimulated growth of MCF-7 cells (IC50, 6 […]

For research use only. We do not sell to patients. Eribulin-d3 mesylate Biological Activity：Eribulin-d3 mesylate is a deuterium labeled Eribulin mesylate. Eribulin mesylate is a microtubule targeting agent that is used for the research of cancer[2]. Research Area：Cancer Targets：Microtubule/Tubulin|Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;Tirbanibulin dihydrochloride;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Tilavonemab;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine D Trending […]

For research use only. We do not sell to patients. HJC0152 hydrochloride CAS No. : 1420290-99-8 Biological Activity：HJC0152 hydrochloride is a signal transducers and activators of transcription 3 (STAT3) inhibitor. Research Area：Cancer Targets：STAT|Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound Library;JAK/STAT Compound Library;Kinase Inhibitor Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Small Molecule Immuno-Oncology […]