Tag: Activator|Inducer

For research use only. We do not sell to patients. Apoptotic agent-3 CAS No. : 2482310-23-4 Biological Activity：Apoptotic agent-3 (compound 15f) promotes apoptosis through the potential mitochondria-mediated Bcl-2/Bax pathway and activation of the Caspase 3 pathway. Apoptotic agent-3 exhibits anti-proliferative activities and can be used for cancer research. Research Area：Cancer Targets：Bcl-2 Family|Caspase|Apoptosis Related Small Molecules:Physalin […]

For research use only. We do not sell to patients. Ezetimibe-d4-1 CAS No. : 1093659-89-2 Biological Activity：Ezetimibe-d4 is deuterium labeled Ezetimibe. Ezetimibe (SCH 58235) is a potent cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator. Research Area：Cardiovascular Disease|Cancer Targets：Autophagy|Keap1-Nrf2 Related Screening Libraries:Bioactive Compound Library Plus; Related Small […]

For research use only. We do not sell to patients. Ambroxol hydrochloride CAS No. : 23828-92-4 Biological Activity：Ambroxol hydrochloride (NA-872 hydrochloride), an active metabolite of the prodrug Bromhexine, has potent expectorant effects. Ambroxol hydrochloride is a glucocerebrosidase (GCase) chaperone and increases glucocerebrosidase activity. Ambroxol hydrochloride induces lung autophagy and has the potential for Parkinson disease […]

For research use only. We do not sell to patients. Traumatic Acid CAS No. : 6402-36-4 Biological Activity：Traumatic Acid is a wound healing agent and a cytokinin (phytohormone). Traumatic Acid enhances the biosynthesis of collagen in cultured human skin fibroblasts. Traumatic Acid inhibits MCF-7 breast cancer cells viability and enhances apoptosis and oxidative stress. Traumatic […]

For research use only. We do not sell to patients. NS-1619 CAS No. : 153587-01-0 Biological Activity：NS-1619 is an opener of large conductance Ca2+-activated K+ (BK) channel. NS-1619 is a highly effective relaxant with an EC50 of about 10 – 30 μM in several smooth muscles of blood vessels and other tissues. NS1619 inhibits proliferation and induces apoptosis […]

For research use only. We do not sell to patients. Destruxin B CAS No. : 2503-26-6 Biological Activity：Destruxin B, isolated from entomopathogenic fungus Metarhizium anisopliae, is one of the cyclodepsipeptides with insecticidal and anticancer activities. Destruxin B induces apoptosis via a Bcl-2 Family-dependent mitochondrial pathway in human nonsmall cell lung cancer cells. Destruxin B significantly […]

For research use only. We do not sell to patients. Bufotalin CAS No. : 471-95-4 Biological Activity：Bufotalin is a steroid lactone isolated from Venenum Bufonis with potently antitumor activities. Bufotalin induces cancer cell apoptosis and also induces endoplasmic reticulum (ER) stress activation[2]. Research Area：Cancer Targets：Reactive Oxygen Species|Apoptosis Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library […]

For research use only. We do not sell to patients. 740 Y-P CAS No. : 1236188-16-1 Biological Activity：740 Y-P (740YPDGFR; PDGFR 740Y-P) is a potent and cell-permeable PI3K activator. 740 Y-P readily binds GST fusion proteins containing both the N- and C- terminal SH2 domains of p85 but fails to bind GST alone. Research Area：Cancer […]

For research use only. We do not sell to patients. Metformin hydrochloride CAS No. : 1115-70-4 Biological Activity：Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) inhibits the mitochondrial respiratory chain in the liver, leading to activation of AMPK, enhancing insulin sensitivity for type 2 diabetes research. Metformin hydrochloride triggers autophagy. Research Area：Metabolic Disease|Cardiovascular Disease Targets：Autophagy|Mitophagy|AMPK Related Screening Libraries:Drug Repurposing […]

For research use only. We do not sell to patients. PAC-1 CAS No. : 315183-21-2 Biological Activity：PAC-1 is a procaspase-3 activator that induces apoptosis in cancer cells with an EC50 of 2.08 μM. Research Area：Cancer Targets：Autophagy|Caspase|Apoptosis Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Autophagy […]