Tag: Activator

For research use only. We do not sell to patients. SOS1 activator 1 CAS No. : 2245237-53-8 Biological Activity：SOS1 activator 1 (Compound 64) is a potent activator of SOS1-mediated nucleotide exchange with a Kd of 44 nM. SOS1 is a guanine nucleotide exchange factor that catalyzes the exchange of GDP for GTP on RAS. Research […]

For research use only. We do not sell to patients. D-Trimannuronic acid CAS No. : 66754-13-0 Biological Activity：D-Trimannuronic acid, an alginate oligomer is extracted from seaweed. D-Trimannuronic acid can induce TNF‐α secretion by mouse macrophage cell lines. D-Trimannuronic acid can be used for the research of pain and vascular dementia[2][3]. Research Area：Inflammation/Immunology|Neurological Disease Targets：TNF Receptor […]

For research use only. We do not sell to patients. Adarotene CAS No. : 496868-77-0 Biological Activity：Adarotene is an effective apoptosis inducer, which surprisingly produces DNA damage and exhibites a potent antiproliferative activity on a large panel of human tumor cells. Research Area：Cancer Targets：Apoptosis Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Anti-Cancer Compound Library;Anti-Blood Cancer […]

For research use only. We do not sell to patients. Fluticasone furoate-d3 Biological Activity：Fluticasone furoate-d3 is deuterium labeled Fluticasone furoate. Fluticasone furoate is a topical, intranasal, enhanced-affinity synthetic trifluorinated corticosteroid with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflamatory and anti-asthmatic activity, and low systemic exposure. Fluticasone furoate has the potential for allergic […]

For research use only. We do not sell to patients. Liriodenine CAS No. : 475-75-2 Biological Activity：Liriodenine (Spermatheridine; VLT045) is an aporphine alkaloid isolated from the plant Mitrephora sirikitiae and has anti-cancer activities. Liriodenine induces cell apoptosis, activates the intrinsic pathway by induction of caspase-3 and caspase-9[2]. Research Area：Cancer Targets：Apoptosis Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase […]

For research use only. We do not sell to patients. Chromenone 1 CAS No. : 1639929-29-5 Biological Activity：Chromenone 1 is a potent osteogenic bone morphogenetic protein (BMP) potentiator. Chromenone 1 exhibits a unique mode of action as it induces a pronounced, kinase-independent, negative TGFβ feedback that enhances nuclear BMP-Smad signaling outputs. Research Area：Others Targets：TGF-β Receptor Related […]

For research use only. We do not sell to patients. MC 1046 CAS No. : 126860-83-1 Biological Activity：MC 1046(Impurity A of Calcipotriol) is an impurity of Calcipotriol; Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors. IC50 value: Target: Vitamin D3 analog that displays minimal effects on calcium homeostasis. Regulates cell differentiation and proliferation; […]

For research use only. We do not sell to patients. 1alpha, 25-Dihydroxy VD2-13C2 Biological Activity：1alpha, 25-Dihydroxy VD2-13C2 is the 13C-labeled 1alpha, 25-Dihydroxy VD2-d6. 1alpha, 25-Dihydroxy VD2-D6 is a deuterated form of vitamin D. Research Area：Metabolic Disease Targets：VD/VDR Related Small Molecules:Atocalcitol;VD3-d6;Dihydrotachysterol;Tacalcitol;Impurity F of Calcipotriol;MeTC7;(24R)-MC 976;VDR agonist 1;TEI-9648;CB1151;MC 1046;Secalciferol;5,6-trans-Vitamin D3;Chol-5-en-24-al-3β-ol;Maxacalcitol-d6;Vitamin D3-13C3;Vitamin D3-D7;Vitamin D4;Vitamin D2-d6 Trending products：Recombinant Proteins  […]

For research use only. We do not sell to patients. Tifenazoxide CAS No. : 279215-43-9 Biological Activity：Tifenazoxide (NN414) is a potent, orally active and SUR1/Kir6.2 selective KATP channels opener. Tifenazoxide has antidiabetic effect, can inhibit glucose stimulated insulin release in vitro and in vivo, and has a beneficial effect on glucose homeostasis[2]. Research Area：Metabolic Disease […]

For research use only. We do not sell to patients. (Rac)-ErSO-DFP CAS No. : 2768139-73-5 Biological Activity：(Rac)-ErSO-DFP is a derivative of ErSO-DFP and a selective small molecule Erα biomodulator. (Rac)-ErSO-DFP againsts ERα+ breast cancer (including resistant tumors) by hyperactiving the Erα-dependent a-UPR (extracted from patent WO2022087234A1). Research Area：Cancer Targets：Estrogen Receptor/ERR Related Small Molecules:DS20362725;LSD1/ER-IN-1;Giredestrant;Avobenzone;Estriol-d3;Chrysin;ERRγ Inverse Agonist […]