Tag: Activator

For research use only. We do not sell to patients. Vanillyl alcohol CAS No. : 498-00-0 Biological Activity：Vanillyl alcohol (p-(Hydroxymethyl)guaiacol), derived from vanillin, is a phenolic alcohol and is used as a flavoring agent in foods and beverages. Research Area：Others Targets：Apoptosis Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Natural Product Library;Fragment Library;Medicine […]

For research use only. We do not sell to patients. TPPB CAS No. : 497259-23-1 Biological Activity：TPPB is a cell-permeable benzolactam-derived protein kinase C (PKC) activator with a Ki of 11.9 nM. Research Area：Neurological Disease Targets：PKC Related Screening Libraries:Bioactive Compound Library Plus; Related Small Molecules:[Ala107]MBP(104-118) TFA;BJE6-106;Myelin Basic Protein;Staurosporine;PKC-iota inhibitor 1;Hypericin;Malantide;PKCiota-IN-2 formic;PF-4950834;C8 Dihydroceramide;SC-9;DL-erythro-Dihydrosphingosine;Safingol;ZIP;Psychosine-d5;Enzastaurin;Protein Kinase C (19-31);Protein […]

For research use only. We do not sell to patients. 20(S)-Hydroxycholesterol CAS No. : 516-72-3 Biological Activity：20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells[2]. Research Area：Cancer Targets：Smo|Endogenous Metabolite Related Screening […]

For research use only. We do not sell to patients. N-Oleoyl glycine CAS No. : 2601-90-3 Biological Activity：N-Oleoyl glycine is a lipoamino acid, which stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte. Research Area：Metabolic Disease Targets：Akt|Endogenous Metabolite|Cannabinoid Receptor Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;GPCR/G Protein […]

For research use only. We do not sell to patients. Benzyl butyl phthalate CAS No. : 85-68-7 Biological Activity：Benzyl butyl phthalate, a member of phthalic acid esters (PAEs), can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1. Benzyl butyl phthalate activates aryl hydrocarbon receptor (AhR) in breast cancer cells to […]

For research use only. We do not sell to patients. Clematichinenoside AR CAS No. : 761425-93-8 Biological Activity：Clematichinenoside AR is a major active ingredient that could be extracted from the traditional Chinese herb Clematis chinensis and has potent pharmacological effects on various diseases, including atherosclerosis (AS). Research Area：Inflammation/Immunology Targets：Autophagy Related Screening Libraries:Natural Product Library Plus;Bioactive […]

For research use only. We do not sell to patients. GN25 CAS No. : 1227401-27-5 Biological Activity：GN25 is a specific p53-Snail binding inhibitor with antitumor effects. Research Area：Cancer Targets：MDM-2/p53 Related Small Molecules:MDM2-p53-IN-15;MC-VC-PABC-SP 141;p53 and MDM2 proteins-interaction-inhibitor (racemic);Navtemadlin;MD-224;Mutant p53 modulator-1;MDM2/4-p53-IN-2;MX69;p-nitro-Pifithrin-α;RG7112;MMRi62;Anticancer agent 50;NSC59984;Pifithrin-β hydrobromide;Ivaltinostat formic;GEM-5;Tenovin-6;PK11007;AM-8735;RO-5963;PhiKan 083;C16-Ceramide;Pifithrin-α hydrobromide;MA242;Anticancer agent 65;CBL0137 hydrochloride;HDAC-IN-34 Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  […]

For research use only. We do not sell to patients. Isosorbide dinitrate CAS No. : 87-33-2 Biological Activity：Isosorbide dinitrate (ISDN) is an NO donor that prevents LV remodeling and degradation of cardiac function following myocardial infarction (MI). Research Area：Cardiovascular Disease Targets：NO Synthase Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive […]

For research use only. We do not sell to patients. TMPA CAS No. : 1258275-73-8 Biological Activity：TMPA is a high-affinity Nur77 antagonist that binds to Nur77 leading to the release and shuttling of LKB1 in the cytoplasm to activate AMPKα. TMPA effectively lowers blood glucose and attenuates insulin resistance in type II db/db, high-fat diet […]

For research use only. We do not sell to patients. Riociguat CAS No. : 625115-55-1 Biological Activity：Riociguat is an oral stimulator of soluble guanylate cyclase (sGC) used in the treatment of pulmonary hypertension. Research Area：Cardiovascular Disease Targets：Guanylate Cyclase Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;GPCR/G Protein […]