Tag: Activator

For research use only. We do not sell to patients. L-Arginine-13C6,15N4 hydrochloride CAS No. : 202468-25-5 Biological Activity：L-Arginine-13C6,15N4 ((S)-(+)-Arginine-13C6,15N4) hydrochloride is the 13C- and 15N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis. Research Area：Others Targets：NO […]

For research use only. We do not sell to patients. NK-252 CAS No. : 1414963-82-8 Biological Activity：NK-252 is a potential Nrf2 activator, which exhibits a great Nrf2-activating potential. Research Area：Cancer Targets：Keap1-Nrf2 Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;NF-κB Signaling Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Antioxidant Compound Library;Oxygen Sensing Compound Library;Ferroptosis […]

For research use only. We do not sell to patients. Ginsenoside Rh3 CAS No. : 105558-26-7 Biological Activity：Ginsenoside Rh3 is a bacterial metabolite of Ginsenoside Rg5. Ginsenoside Rh3 treatment in human retinal cells induces Nrf2 activation. Research Area：Inflammation/Immunology Targets：Keap1-Nrf2 Related Screening Libraries:Natural Product Library Plus; Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;NF-κB Signaling Compound Library;Stem Cell […]

For research use only. We do not sell to patients. Dehydroeffusol CAS No. : 137319-34-7 Biological Activity：Dehydroeffusol is a phenanthrene from medicinal herb Juncus effuses. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. It shows very low toxicity[2]. Research Area：Cancer Targets：Apoptosis Related Screening Libraries:Natural […]

For research use only. We do not sell to patients. SRT 2104 CAS No. : 1093403-33-8 Biological Activity：SRT 2104 is a first-in-class, highly selective and brain-permeable activator of the NAD+ dependent deacetylase Sirt1, increases Sirt1 protein, but shows no effect on Sirt1 mRNA. Used in the research of diabetes mellitus and Huntington’s disease[2][3]. Research Area：Metabolic […]

For research use only. We do not sell to patients. Phe-Met-Arg-Phe amide trifluoroacetate CAS No. : 159237-99-7 Biological Activity：Phe-Met-Arg-Phe amide trifluoroacetate is an activator of K+ current, with ED50 of 23 nM in the peptidergic caudodorsal neurons. Research Area：Neurological Disease Targets：Potassium Channel Related Screening Libraries:Bioactive Compound Library Plus;Peptide Library; Related Small Molecules:Kv3 modulator 2;Brompheniramine-d6 maleate;Pinacidil;AMP-PNP […]

For research use only. We do not sell to patients. Omecamtiv mecarbil-d8 Biological Activity：Omecamtiv mecarbil-d8 (CK-1827452-d8) is the deuterium labeled Omecamtiv mecarbil. Omecamtiv mecarbil (CK-1827452) is a selective cardiac myosin activator. Research Area：Cardiovascular Disease Targets：Myosin Related Small Molecules:MLCK inhibitor peptide 18;Danicamtiv;W-7 hydrochloride;Mavacamten;HA-100 hydrochloride;BTS;ATM-3507;MS-444;(-)-Blebbistatin;MT-134;Pentachloropseudilin;ML-7 hydrochloride;ML-9;para-Nitroblebbistatin;Omecamtiv mecarbil;Biacetyl monoxime;Aficamten Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural […]

For research use only. We do not sell to patients. Curcumol CAS No. : 4871-97-0 Biological Activity：Curcumol ((-)-Curcumol), a bioactive sesquiterpenoid, possesses numerous pharmacological activities like anticancer, antimicrobial, antifungal, antiviral, and antiinflammatory. Curcumol is a potent inducer of apoptosis in numerous cancer cells via targeting key signaling pathways as MAPK/ERK, PI3K/Akt and NF-κB which are […]

For research use only. We do not sell to patients. Synephrine hemitartrate CAS No. : 16589-24-5 Biological Activity：Synephrine (Oxedrine) hemitartrate, an alkaloid, is an α-adrenergic and β-adrenergic agonist derived from the Citrus aurantium. Synephrine hemitartrate is a sympathomimetic compound and can be used for weight loss[2]. Research Area：Neurological Disease Targets：Adrenergic Receptor|Endogenous Metabolite Related Small Molecules:D-α-Hydroxyglutaric […]

For research use only. We do not sell to patients. PD146176 CAS No. : 4079-26-9 Biological Activity：PD146176 (NSC168807), a 15-Lipoxygenase (15-LO) inhibitor, inhibits rabbit reticulocyte 15-LO (Ki=197 nM, IC50=0.54 μM). PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice[2][3]. Research Area：Cardiovascular Disease Targets：Ferroptosis|Autophagy Related Screening Libraries:Bioactive Compound […]