Epigenetics-modulation-frontier

Master of Bioactive Molecules | Inhibitors, Screening Libraries & Proteins

Ambroxol

Product Name : AmbroxolDescription:Ambroxol (NA-872), an active metabolite of the prodrug Bromhexine, has potent expectorant effects. Ambroxol is a glucocerebrosidase (GCase) chaperone and increases glucocerebrosidase activity. Ambroxol induces lung autophagy and has the potential for Parkinson disease and neuronopathic Gaucher disease research.CAS: 18683-91-5Molecular Weight:378.10Formula: C13H18Br2N2OChemical Name: 4-{[(2-amino-3,5-dibromophenyl)methyl]amino}cyclohexan-1-olSmiles : NC1C(Br)=CC(Br)=CC=1CNC1CCC(O)CC1InChiKey: JBDGDEWWOUBZPM-UHFFFAOYSA-NInChi : InChI=1S/C13H18Br2N2O/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10/h5-6,10-11,17-18H,1-4,7,16H2Purity: ≥98% (or refer […]

D-Arginine

Product Name : D-ArginineDescription:D-arginine (H-D-Arg-OH) is the D-isomer of arginine. Arginine is an α-amino acid that is used in the biosynthesis of proteins. D-Arginine is an inactive form of L-arginine.CAS: 157-06-2Molecular Weight:174.20Formula: C6H14N4O2Chemical Name: (2R)-2-amino-5-[(diaminomethylidene)amino]pentanoic acidSmiles : NC(N)=NCCC[C@@H](N)C(O)=OInChiKey: ODKSFYDXXFIFQN-SCSAIBSYSA-NInChi : InChI=1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m1/s1Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as […]

Manninotriose

Product Name : ManninotrioseDescription:Manninotriose is a novel and important player in the RFO(Raffinose family oligosaccharides) metabolism of red dead deadnettle; potential to improve the side effects of MTX for ALL treatment.CAS: 13382-86-0Molecular Weight:504.44Formula: C18H32O16Chemical Name: (2R,3S,4R,5R)-2,3,4,5-tetrahydroxy-6-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-({[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}hexanalSmiles : OC[C@H]1O[C@H](OC[C@H]2O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)[C@H](O)[C@@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1OInChiKey: FZWBNHMXJMCXLU-YRBKNLIBSA-NInChi : InChI=1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2/t5-,6+,7+,8+,9+,10+,11-,12-,13-,14-,15+,16+,17-,18-/m0/s1Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as […]

PROTAC ERRα ligand 1

Product Name : PROTAC ERRα ligand 1Description:PROTAC ERRα ligand 1 is an estrogen-related receptor α (ERRα) antagonist with IC50s of 0.04 and 2.8 μM for ERRα and ERRγ, respectively.CAS: 1264754-13-3Molecular Weight:420.36Formula: C19H11F3N2O4SChemical Name: 4-(4-{[(5Z)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}-2-methoxyphenoxy)-3-(trifluoromethyl)benzonitrileSmiles : COC1=CC(=CC=C1OC1=CC=C(C=C1C(F)(F)F)C#N)/C=C1\SC(=O)NC\1=OInChiKey: OBBIOCQFTMNSJI-PXNMLYILSA-NInChi : InChI=1S/C19H11F3N2O4S/c1-27-15-7-10(8-16-17(25)24-18(26)29-16)2-5-14(15)28-13-4-3-11(9-23)6-12(13)19(20,21)22/h2-8H,1H3,(H,24,25,26)/b16-8-Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical […]

Josamycin solution, 10 µg/ml in acetone

Product Name : Josamycin solution, 10 µg/ml in acetoneSynonym: Kitasamycin A3 , Leucomycin A3 , Turimycin A5CAS : 16846-24-5Molecular formula:C42H69NO15Molecular Weight : 827.{{2369751-07-3} web|{2369751-07-3} Biological Activity|{2369751-07-3} In Vivo|{2369751-07-3} supplier} 99Purity: ≥98% (UV)Specifications: Purity ≥98% (UV)|Appearance White to off-white powder|Identity 1H-NMR|Concentration 10 µg/ml in acetone|PropertiesSolvents water|{{1448347-49-6} medchemexpress|{1448347-49-6} Purity & Documentation|{1448347-49-6} Description|{1448347-49-6} manufacturer} PMID:30000051 MedChemExpress (MCE) offers […]

Schisantherin E

Product Name : Schisantherin EDescription:Schisantherin E is a natural compound isolated from the active fraction of the fruits of Schisandra sphenanthera Rehd. et Wils.CAS: 64917-83-5Molecular Weight:538.59Formula: C30H34O9Chemical Name: (8S,9S,10S)-9,14-dihydroxy-3,4,5,15,16-pentamethoxy-9,10-dimethyltricyclo[10.4.0.0²,⁷]hexadeca-1(16),2,4,6,12,14-hexaen-8-yl benzoateSmiles : C[C@H]1CC2=CC(O)=C(OC)C(OC)=C2C2=C(OC)C(OC)=C(C=C2[C@H](OC(=O)C2C=CC=CC=2)[C@@]1(C)O)OCInChiKey: ZNXDFTKQSCEJGE-DSASHONVSA-NInChi : InChI=1S/C30H34O9/c1-16-13-18-14-20(31)24(35-4)26(37-6)22(18)23-19(15-21(34-3)25(36-5)27(23)38-7)28(30(16,2)33)39-29(32)17-11-9-8-10-12-17/h8-12,14-16,28,31,33H,13H2,1-7H3/t16-,28-,30-/m0/s1Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate […]

DAF-2 DA

Product Name : DAF-2 DASynonym: 4,5-Diaminofluorescein diacetate , 5,6-Diaminofluorescein diacetateCAS : 205391-02-2Molecular formula:C24H18N2O7Molecular Weight : 446.{{1627503-67-6} site|{1627503-67-6} Biological Activity|{1627503-67-6} Data Sheet|{1627503-67-6} custom synthesis} 41Purity: ≥95% (HPLC)Specifications: Purity ≥95% (HPLC)|Appearance Off-white powder|Identity 1H-NMR|PropertiesSolvents DMSO|Fluorescence λex 491 nm, λem 513 nm|DownloadsSafety Data Sheet CDX D0085 MSDS.{{1799631-75-6} web|{1799631-75-6} Biological Activity|{1799631-75-6} Data Sheet|{1799631-75-6} manufacturer} pdf|PMID:22876374 MedChemExpress (MCE) offers a […]

Alcaftadine-D3

Product Name : Alcaftadine-D3Description:Alcaftadine-D3 (R89674-D3) is a deuterium labeled Alcaftadine. Alcaftadine (HY-17039) is a H1 histamine receptor antagonist.CAS: 1794775-80-6Molecular Weight:310.41Formula: C19H21N3OChemical Name: 2-[1-(²H₃)methylpiperidin-4-ylidene]-4,7-diazatricyclo[8.4.0.0³,⁷]tetradeca-1(14),3,5,10,12-pentaene-6-carbaldehydeSmiles : [2H]C([2H])([2H])N1CCC(CC1)=C1C2=NC=C(C=O)N2CCC2=CC=CC=C21InChiKey: MWTBKTRZPHJQLH-FIBGUPNXSA-NInChi : InChI=1S/C19H21N3O/c1-21-9-6-15(7-10-21)18-17-5-3-2-4-14(17)8-11-22-16(13-23)12-20-19(18)22/h2-5,12-13H,6-11H2,1H3/i1D3Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of AnalysisStorage Condition : Dry, dark and […]

10-Acetylphenothiazine

Product Name : 10-AcetylphenothiazineSynonym: 10-Acetyl-10H-phenothiazine, 1-(10H-Phenothiazin-10-yl)ethanone, NSC 14724, J 3-55CAS : 1628-29-1Molecular formula:C14H11NOSMolecular Weight : 241.{{2797026-97-0} site|{2797026-97-0} Protocol|{2797026-97-0} In Vitro|{2797026-97-0} custom synthesis} 31Purity: ≥95% (NMR)Specifications: Purity ≥95% (NMR)|Appearance Beige powder|Identity 1H-NMR|PropertiesSolvents chloroform|{{6090-95-5} MedChemExpress|{6090-95-5} Protocol|{6090-95-5} In Vitro|{6090-95-5} custom synthesis} PMID:30571052 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference […]

4-Acetamido-5-nitrophthalic anhydride

Product Name : 4-Acetamido-5-nitrophthalic anhydrideSynonym: N-(1,3-Dihydro-6-nitro-1,3-dioxo-5-isobenzofuranyl)acetamide , N-(6-Nitro-1,3-dioxo-1,3-dihydroisobenzofuran-5-yl)acetamideCAS : 209324-72-1Molecular formula:C10H6N2O6Molecular Weight : 250.{{2229047-91-8} site|{2229047-91-8} Biological Activity|{2229047-91-8} Formula|{2229047-91-8} custom synthesis} 16Purity: ≥98% (GC)Specifications: Purity ≥98% (GC)|Appearance Yellow crystals|Identity 1H-NMR|PropertiesSolvents DMSO|Melting Point 177-179°C|DownloadsSafety Data Sheet CDX A0245 MSDS.{{4800-94-6} web|{4800-94-6} Biological Activity|{4800-94-6} Formula|{4800-94-6} supplier} pdf|PMID:29489283 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals […]