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RSV/IAV-IN-3

CAS No. : 2395007-81-3

Biological Activity：RSV/IAV-IN-3 (compound 14’i) is a dual inhibitor of respiratory syncytial virus (RSV) and influenza A virus (IAV) with EC₅₀ values of 2.92 µM and 1.90 µM,respectively. RSV/IAV-IN-3 has antiviral effect against H1N1 and H3N2 with EC₅₀ values of 3.25 µM and 1.50 µM in MDCK cells, respectively. RSV/IAV-IN-3 significantly inhibits the activity of luciferase in a dose-dependent manner, with an EC₅₀ of 3.89 µM. RSV/IAV-IN-3 inhibits IAV infectivity and RdRp activity. RSV/IAV-IN-3 inhibits IAV and RSV replication at the post-entry stage.

Research Area：Infection

Targets：Influenza Virus|RSV

Related Small Molecules:Quercetin pentaacetate;Curcumin;(R)-Camptothecin-d5;Glaucine;Hypericin;Neuraminidase-IN-3;FGI-106 tetrahydrochloride;Molnupiravir;Onradivir;SP187;Nuezhenidic acid;Ketotifen fumarate;Baloxavir-d5;Coptisine chloride;RSV604 (R enantiomer);Ginsenoside Rb2;T-1105;Tetrahydroepiberberine;JNJ4796;Loratadine-d5;Camptothecin;Eriodictyol;Catechin-13C3;Dendrobine;N-Glycolylneuraminic acid

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