January 12, 2023 - epigenetics modulation frontier

DL-Serine-2,3,3-d3

Posted on January 12, 2023 by haoyuan2014

For research use only. We do not sell to patients. DL-Serine-2,3,3-d3 CAS No. : 70094-78-9 Biological Activity：DL-Serine-2,3,3-d3 is the deuterium labeled DL-Serine. DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV). Research Area：Cancer|Infection Targets：Others|TMV Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin […]

NLRP3 modulators 1

Posted on January 12, 2023 by haoyuan2014

For research use only. We do not sell to patients. NLRP3 modulators 1 CAS No. : 2143015-87-4 Biological Activity：NLRP3 modulators 1 is the potent modulator of NLRP3. NLRP3 modulators 1 agonizes or partially agonizes NLRP3 that are useful for researching a condition, disease or disorder in which a decrease in LRP3 activity contributes to the […]

Tiragolumab

Posted on January 12, 2023 by haoyuan2014

For research use only. We do not sell to patients. Tiragolumab CAS No. : 1918185-84-8 Biological Activity：Tiragolumab is an immune checkpoint inhibitor binding to T-cell immunoglobulin and ITIM domain (TIGIT). Tiragolumab, alone or in combination with the PD-L1 inhibitor Atezolizumab, may be effective against multiple solid malignancies-most notably non-small cell lung cancer[2]. Research Area：Cancer|Inflammation/Immunology Targets：Others […]

MA-0204

Posted on January 12, 2023 by haoyuan2014

For research use only. We do not sell to patients. MA-0204 CAS No. : 2095128-17-7 Biological Activity：MA-0204 is a potent, highly selective and orally available peroxisome proliferator activated receptor δ (PPARδ) modulator with EC50s of 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARδ, respectively. Potential treatment for Duchene Muscular Dystrophy […]

Diphyllin

Posted on January 12, 2023 by haoyuan2014

For research use only. We do not sell to patients. Diphyllin CAS No. : 22055-22-7 Biological Activity：Diphyllin is an arylnaphthalene lignan isolated from Justicia procumbens and is a potent HIV-1 inhibitor with an IC50 of 0.38 μM. Diphyllin is active against vesicular stomatitis virus (VSV) and influenza virus. Diphyllin is a vacuolar type H+-ATPase (V-ATPase) […]

3-Bromocytisine

Posted on January 12, 2023 by haoyuan2014

For research use only. We do not sell to patients. 3-Bromocytisine CAS No. : 207390-14-5 Biological Activity：3-Bromocytisine (3-Br-cytisine) is a potent nACh receptors agonist, with IC50s are 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7-nACh, respectively. 3-Bromocytisine (3-Br-cytisine) shows different effects on high (HS) and low (LS) ACh sensitivity α4β2 nAChRs with EC50s […]

Dihydrexidine

Posted on January 12, 2023 by haoyuan2014

For research use only. We do not sell to patients. Dihydrexidine CAS No. : 123039-93-0 Biological Activity：Dihydrexidine (DAR-0100) is a high potent, selective and full efficacy D1-like dopamine receptor (D1/D5) agonist with an IC50 of 10 nM for D1 receptor. Dihydrexidine exhibits potent antiparkinsonian activity[2][3][4]. Dihydrexidine can stimulate YAP phosphorylation[5]. Research Area：Neurological Disease Targets：Dopamine Receptor […]

Lenalidomide-propargyl-C2-amido-Ph-NH2 hydrochloride

Posted on January 12, 2023 by haoyuan2014

For research use only. We do not sell to patients. Lenalidomide-propargyl-C2-amido-Ph-NH2 hydrochloride Biological Activity：Lenalidomide-propargyl-C2-amido-Ph-NH2 hydrochloride incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase and a linker. Lenalidomide-propargyl-C2-amido-Ph-NH2 hydrochloride can be used to design the PROTAC MD-224 (HY-114312). Research Area：Cancer Targets：E3 Ligase Ligand-Linker Conjugates Related Small Molecules:cIAP1 Ligand-Linker Conjugates 6 hydrochloride;(S,R,S)-AHPC-Me-C10-NH2;cIAP1 Ligand-Linker Conjugates 2;Glutarimide-Isoindolinone-NH-PEG3-COOH;cIAP1 […]

Cilastatin-15N,d3

Posted on January 12, 2023 by haoyuan2014

For research use only. We do not sell to patients. Cilastatin-15N,d3 CAS No. : 2738376-83-3 Biological Activity：Cilastatin-15N,d3 is a 15N-labeled and deuterium labeled Cilastatin. Cilastatin (MK0791) is a reversible, competitive renal dehydropeptidase I inhibitor with an IC50 of 0.1 μM. Cilastatin inhibits the bacterial metallob-lactamase enzyme CphA with an IC50 of 178 μM. Cilastatin is […]

Urapidil-d3

Posted on January 12, 2023 by haoyuan2014

For research use only. We do not sell to patients. Urapidil-d3 CAS No. : 1398066-08-4 Biological Activity：Urapidil-d3 is the deuterium labeled Urapidil. Urapidil is an α1 adrenoreceptor antagonist and a 5-HT1A receptor agonist. Research Area：Neurological Disease|Endocrinology Targets：Adrenergic Receptor|5-HT Receptor Related Small Molecules:F 13714;Mosapride-d5;Todralazine;ARC 239 dihydrochloride;Nuciferine;Yohimbine;Glaucine;Salbutamol;Renzapride;BI-167107;LY 344864 racemate;Harmine hydrochloride;Talibegron hydrochloride;Valerenic acid;Arotinolol;SR59230A;Melitracen-d6 hydrochloride;WAY-100635 Trending products：Recombinant Proteins | […]