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Remogliflozin etabonate
CAS No. : 442201-24-3
Biological Activity：Remogliflozin etabonate (GSK189075) is an orally active, selective and low-affinity sodium glucose cotransporter (SGLT2) inhibitor with Ki values of 1.95 μM, 2.14 μM, 43.1 μM, 8.57 μM for hSGLT2, rSGLT2, hSGLT1, rSGLT1, respectively. Remogliflozin etabonate is a prodrug based on benzylpyrazole glucoside and is metabolized to its active form, Remogliflozin, in the body. Remogliflozin etabonate exhibits antidiabetic efficacy in rodent models.
Research Area：Metabolic Disease
Targets：SGLT
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Anti-diabetic Compound Library;Glycoside Compound Library;Orally Active Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Targeted Diversity Library;
Related Small Molecules:Luseogliflozin;SGL5213;Tofogliflozin;Mizagliflozin;Trilobatin;TA-1887;SGLT inhibitor-1;Sotagliflozin;Phloretin;Ertugliflozin L-pyroglutamic acid;Ipragliflozin (L-Proline);LX2761;Enavogliflozin;T-1095;HSK0935;Ipragliflozin-d5;Velagliflozin;Kushenol K
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