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DCP-LA
CAS No. : 28399-31-7
Biological Activity：DCP-LA (FR236924), a linoleic acid derivative, selectively and directly activates PKCε. DCP-LA activates Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) and inhibits protein phosphatase-1 (PP-1) to stimulate AMPA receptor exocytosis. DCP-LA inhibits activation of caspase-3/-9 and protects neurons at least in part from oxidative stress-induced apoptosis[2][3].
Research Area：Neurological Disease
Targets：PKC|CaMK|Phosphatase|Apoptosis
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