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187-1, N-WASP inhibitor
CAS No. : 380488-27-7
Biological Activity：187-1, N-WASP inhibitor, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC50 of 2 μM. 187-1, N-WASP inhibitor prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein[2].
Research Area：Others
Targets：Arp2/3 Complex
Related Small Molecules:Wiskostatin;CK-869;Jasplakinolide;Dihydrocytochalasin B;SMIFH2;CK-636;Cytochalasin B;187-1, N-WASP inhibitor TFA;Phalloidin-TRITC;CK-666;Cytochalasin D;Latrunculin A;Phallacidin;19-O-Acetylchaetoglobosin A;LKKTETQ
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