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IMR-1A
CAS No. : 331862-41-0
Biological Activity：IMR-1A, a acid metabolite of IMR-1, is a Notch inhibitor with an IC50 of 0.5 μM. IMR-1A has a 50-fold increase in potency with respect to IMR-1. IMR-1 can metabolize in vivo to IMR-1A.
Research Area：Cancer
Targets：Drug Metabolite|Notch
Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Neuronal Signaling Compound Library;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Differentiation Inducing Compound Library;Anti-Breast Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Angiogenesis-Related Compound Library;Transcription Factor-Targeted Library;Drug Metabolite Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Cancer Stem Cells Compound Library;
Related Small Molecules:Nicotinamide N-oxide;ZLDI-8;4-Hydroxyphenylbutazone;Ampyrone;Resveratrol-3-O-sulfate sodium;Sonidegib metabolite M48;Crenigacestat;Isonicotinic acid;Cycloguanil hydrochloride;Hydroxytanshinone IIA;FLI-06;Endoxifen;Fodipir;Regorafénib N-oxyde (M2)-13C,d3;AZ7550 Mesylate
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