Master of Bioactive Molecules | Inhibitors, Screening Libraries & Proteins
Deep learning is a subset of artificial intelligence (AI) that mimics the neural networks of the human brain to learn from large amounts of data, enabling machines to solve complex problems. Deep learning technology has made significant progress in the biomedical field. Researchers have developed a series of application based on deep learning for disease […]
Product Name : ZYZ-488Description:ZYZ-488 is a competitive apoptotic protease activating factor-1 (Apaf-1) inhibitor. ZYZ-488 inhibits the activation of binding protein procaspase-9 and procaspase-3.CAS: 1470302-79-4Molecular Weight:487.46Formula: C20H29N3O11Chemical Name: (2S, 3S, 4S, 5R, 6S)-6-4-[(4-carbamimidamidobutoxy)carbonyl]-2, 6-dimethoxyphenoxy-3, 4, 5-trihydroxyoxane-2-carboxylic acidSmiles : COC1=CC(=CC(OC)=C1O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O)C(=O)OCCCCNC(N)=NInChiKey: PVTAIJDQJJZCJP-WXZWTWHISA-NInChi : InChI=1S/C20H29N3O11/c1-30-10-7-9(18(29)32-6-4-3-5-23-20(21)22)8-11(31-2)15(10)33-19-14(26)12(24)13(25)16(34-19)17(27)28/h7-8,12-14,16,19,24-26H,3-6H2,1-2H3,(H,27,28)(H4,21,22,23)/t12-,13-,14+,16-,19+/m0/s1Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as […]
Product Name : PTX3 (human), (recombinant)Sequence: Purity: Molecular Weight:~42kDa. Due to glycosylation, PTX3 may migrate between 40-45kDa.Solubility : Appearance: Use/Stability : Description: CAS : Solubility: Formula: Additional Information : | Alternative Name Pentraxin 3, TSG14, TNF stimulated gene-14 | Application Notes ELISA and Western blot standard together with MAb to PTX3 ) and PAb to […]
Product Name : Ginsenoside Rh2Description:Ginsenoside Rh2 is isolated from the root of Ginseng. Ginsenoside Rh2 induces the activation of caspase-8 and caspase-9. Ginsenoside Rh2 induces cancer cell apoptosis in a multi-path manner.CAS: 78214-33-2Molecular Weight:622.87Formula: C36H62O8Chemical Name: (2R, 3R, 4S, 5S, 6R)-2-{[(1S, 3aR, 3bR, 5aR, 7S, 9aR, 9bR, 11R, 11aR)-11-hydroxy-1-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-3a, 3b, 6, 6, 9a-pentamethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-7-yl]oxy}-6-(hydroxymethyl)oxane-3, 4, 5-triolSmiles […]
Product Name : PDK1 polyclonal antibodySequence: Purity: Molecular Weight:Solubility : Appearance: Use/Stability : Description: PDK-1 (Pyruvate dehydrogenase kinase-1) is a 48 kDa protein kinase. It is a member of the mitrochondrial matrix protein kinase family and is related to the histidine protein kinases found in prokaryotes. PDK-1 is responsible for phosphorylation and concomitant inactivation of […]
Product Name : Polyphyllin IDescription:Polyphyllin I is a bioactive constituent extracted from Paris polyphylla, has strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and is an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis.CAS: 50773-41-6Molecular Weight:855.02Formula: C44H70O16Chemical Name: (2S, 3R, 4R, 5R, 6S)-2-[(2R, 3R, 4S, […]
Product Name : Meloxicam-d3Description:Meloxicam-d3 is deuterium labeled Meloxicam. Meloxicam is a non-steroidal antiinflammatory agent, inhibits COX activity, with IC50s of 0.49 µM and 36.6 µM for COX-2 and COX-1, respectively.CAS: 942047-63-4Molecular Weight:354.42Formula: C14H13N3O4S2Chemical Name: 4-hydroxy-2-(²H₃)methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-2H-1λ⁶,2-benzothiazine-3-carboxamideSmiles : [2H]C([2H])([2H])N1C(=C(O)C2=CC=CC=C2S1(=O)=O)C(=O)NC1=NC=C(C)S1InChiKey: ZRVUJXDFFKFLMG-BMSJAHLVSA-NInChi : InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19)/i2D3Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous […]
Product Name : Myeloperoxidase (human leukocytes)Sequence: Purity: ≥98%Molecular Weight:Solubility : Appearance: Green solidUse/Stability : As indicated on product label or CoA when stored as recommended. Stored at -20°C this product is stable for years.Storage of the reconstituted form at 4°C for 2 weeks has no effect on enzyme activity. If solutions must be stored for […]
Product Name : Triazolomethylindole-3-aceticacid-d5Description:Product informationCAS: 1216889-22-3Molecular Weight:261.29Formula: C13H12N4O2Chemical Name: 2-{5-[(1H-1,2,4-triazol-1-yl)(²H₂)methyl](4,6,7-²H₃)-1H-indol-3-yl}acetic acidSmiles : [2H]C1C2C(CC(O)=O)=CNC=2C([2H])=C([2H])C=1C([2H])([2H])N1C=NC=N1InChiKey: KACIHDPNKNLLMA-JZOBIDBQSA-NInChi : InChI=1S/C13H12N4O2/c18-13(19)4-10-5-15-12-2-1-9(3-11(10)12)6-17-8-14-7-16-17/h1-3,5,7-8,15H,4,6H2,(H,18,19)/i1D,2D,3D,6D2Purity: ≥98% (or refer to the Certificate of Analysis)Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of AnalysisStorage Condition : Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Streptomycin} […]
Product Name : LIMK2 monoclonal antibody (10E5-19)Sequence: Purity: Molecular Weight:Solubility : Appearance: Use/Stability : Stable for at least 1 year after receipt when stored at -20°C.Description: The LIM kinases 1 and 2 (LIMK1 and LIMK2) are activated downstream of the Rho-ROCK, Rac-PAK, and Cdc42-MRCK pathways, thereby acting as network nodes in the signaling pathways that […]