Product Name :
CD47 Recombinant Rabbit Monoclonal Antibody [PD00-33]
Predicted band size :
Observed band size :
Synonyms:
Antigen identified by monoclonal antibody 1D8 antibody Antigenic surface determinant protein OA3 antibody CD 47 antibody CD47 antibody CD47 antigen (Rh-related antigen, integrin-associated signal transducer) antibody CD47 antigen antibody CD47 glycoprotein antibody CD47 molecule antibody CD47_HUMAN antibody IAP antibody 展开
Function :
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα). Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. CD47 is involved in a range of cellular processes, including apoptosis, proliferation, adhesion, and migration. Furthermore, it plays a key role in immune and angiogenic responses. CD47 is ubiquitously expressed in human cells and has been found to be overexpressed in many different tumor cells. Expression in equine cutaneous tumors has been reported as well.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human CD47 aa 50-150 (internal sequence).
Species reactivity:
Human
Verify application:
IHC-P, FC
Coupling :
unconjugated
Clone number:
PD00-33
RRID:
AB_3072280
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Dapagliflozin Aliquot store at -20℃.Melatonin Avoid repeated freeze / thaw cycles.PMID:28630660
Storage buffer solution:
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 35 kDa
Positive control :
Human ovarian tumor tissue, human prostate tissue, Jurkat.