Product Name :
CD35 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
C3 binding protein antibody C3b/C4b receptor antibody C3BR antibody C4BR antibody CD 35 antibody CD35 antibody CD35 antigen antibody complement component (3b/4b) receptor 1 (Knops blood group) antibody complement component (3b/4b) receptor 1 including Knops blood group system antibody Complement component receptor 1 antibody 展开
Function :
Membrane immune adherence receptor that plays a critical role in the capture and clearance of complement-opsonized pathogens by erythrocytes and monocytes/macrophages .Clotrimazole Mediates the binding by these cells of particles and immune complexes that have activated complement to eliminate them from the circulation . Acts also in the inhibition of spontaneous complement activation by impairing the formation and function of the alternative and classical pathway C3/C5 convertases, and by serving as a cofactor for the cleavage by factor I of C3b to iC3b, C3c and C3d,g, and of C4b to C4c and C4d. Plays also a role in immune regulation by contributing, upon ligand binding, to the generation of regulatory T cells from activated helper T cells .
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Recombinant protein within human Complement receptor type 1 aa 600-800.Rosmarinic acid
Species reactivity:
Human
Verify application:
WB, IHC-P, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3069493
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:28322188 Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 224 kDa
Positive control :
HL-60 cell lysates, recombinant protein lysates, human spleen tissue, human kidney tissue, Daudi.