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Enpp/Carbonic anhydrase-IN-1
Biological Activity:Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent Enpp and carbonic anhydrase inhibitor with IC50s of 1.36, 1.35, 3.00, 0.88, 1.02 µM for NPP1, NPP2, NPP3, CA-II, CA-IX respectively. Enpp/Carbonic anhydrase-IN-1 shows antiproliferative activity for cancer cells and low cytotoxic against normal cells. Enpp/Carbonic anhydrase-IN-1 induces (< a href="apoptosis" class="link-product" target="_blank">apoptosis a>).
Research Area:Cancer
Targets:Phosphodiesterase (PDE)|Carbonic Anhydrase|Apoptosis
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