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CAS No. : 2769753-47-9

Biological Activity:DB0614 (Example 21) is a bifunctional compound targeted protein degradation of kinases. DB0614 degrades AAK1, AURKA, BMP2K, CAMKK1, CDK16, CML, CDK6, EIF2AK2, FER, GAK, LCK, LIMK2, MAP3KH, MAPK8, MAPK9, NEK9, PLK4, PTK2B, SIK2, STK17A, STK17B, ULK1, ULK3, and WEE1. DB0614 can be used for research of disease or disorder mediated by aberrant kinase activity.

Research Area:Others

Targets:Ferroptosis|CDK|CaMK|ULK|Aurora Kinase|Salt-inducible Kinase (SIK)|PROTACs|AAK1|Wee1|LIM Kinase (LIMK)

Related Small Molecules:PROTAC Sirt2 Degrader-1;CIL56;Dinaciclib;AT9283;SNS-032;CC-671;Ciclopirox-d11;Ciclopirox olamine;PROTAC VEGFR-2 degrader-2;Curcumin;(E/Z)-Zotiraciclib;dTAGV-1-NEG;CCT367766 formic;CDK1-IN-4;CCT-251921;BS-181;SGC-AAK1-1;Samuraciclib hydrochloride hydrate;T025;HDAC6 degrader-1;Flavopiridol;CDK8-IN-3;PROTAC Axl Degrader 2;PhosTAC7;CDK9-IN-12;MS98;FLT3/CDK4-IN-1

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