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Chlorpropamide
CAS No. : 94-20-2
Biological Activity：Chlorpropamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).
Target:
Chlorpropamide belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin.Chlorpropamide is not recommended for the treatment of NIDDM as it increases blood pressure and the risk of retinopathy. Up to 80% of the single oral dose of chlorpropramide is metabolized, likely in the liver; 80-90% of the dose is excreted in urine as unchanged drug and metabolites.
Research Area：Endocrinology
Targets：Na+/K+ ATPase
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;FDA-Approved Drug Library;Drug Repurposing Compound Library;Anti-diabetic Compound Library;Endocrinology Compound Library;NMPA-Approved Drug Library;FDA Approved & Pharmacopeial Drug Library;Drug-Induced Liver Injury (DILI) Compound Library;Human Metabolite Library;
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