For research use only. We do not sell to patients.

Ceritinib

CAS No. : 1032900-25-6

Biological Activity：Ceritinib (LDK378) is a selective, orally bioavailable, and ATP-competitive ALK tyrosine kinase inhibitor with an IC₅₀ of 200 pM. Ceritinib (LDK378) also inhibits IGF-1R, InsR, and STK22D with IC₅₀ values of 8, 7, and 23 nM, respectively. Ceritinib (LDK378) shows great antitumor potency^[2].

Research Area：Cancer|Endocrinology

Targets：Insulin Receptor|IGF-1R|Anaplastic lymphoma kinase (ALK)

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Differentiation Inducing Compound Library;Endocrinology Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Lung Cancer Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Targeted Therapy Drug Library ;Angiogenesis-Related Compound Library;Rare Diseases Drug Library;EMA-Approved Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Non-steroidal Anti-Inflammatory Compound Library;

Related Small Molecules:ALK-IN-9;KRCA-0008;AGL-2263;Alectinib-d8;MS4078;TL13-22;AZ7550 Mesylate;KU14R;NVP-TAE 684;Picropodophyllotoxin-d6;SU4984;Chromeceptin;ALK5-IN-30;TL13-112;I-OMe-Tyrphostin AG 538;ALK-IN-22;Ganitumab;HNMPA-(AM)3;Alectinib;ALK-IN-12;S961 TFA;OI338;Entrectinib;ALK kinase inhibitor-1

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides

About Us:

• MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
• Structurally and synthetically diverse biologically active compounds；
•  roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
• We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
• Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；

Structurally and synthetically diverse biologically active compounds；

• Customized order volume ranging from milligrams to kilograms scale；

We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.