Ursodeoxycholic acid sodium

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Ursodeoxycholic acid sodium

CAS No. : 2898-95-5

Biological Activity:Ursodeoxycholic acid (Ursodeoxycholate) sodium is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid sodium acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid sodium can be used for the research of a variety of hepatic and gastrointestinal diseases. Orally active[2].

Research Area:Cancer|Metabolic Disease|Inflammation/Immunology

Targets:FXR|Endogenous Metabolite|G protein-coupled Bile Acid Receptor 1

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