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SW157765

CAS No. : 332063-87-3

Biological Activity：SW157765 is a selective non-canonical glucose transporter GLUT8 (SLC2A8) inhibitor. KRAS/KEAP1 double mutant NSCLC cells are selectively sensitive to the SW157765, due to the convergent consequences of dual KRAS and NRF2 modulation of metabolic and xenobiotic gene regulatory programs^[2].

Research Area：Cancer

Targets：GLUT

Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;NF-κB Signaling Compound Library;Anti-Cancer Compound Library;Glycolysis Compound Library;Glutamine Metabolism Compound Library;Anti-Lung Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Glucose Metabolism Compound Library;

Related Small Molecules:Sennidin A;Licarin B;GLUT4 activator 1;GLUT4-IN-2;STF-31;KPH2f;BAY-876;MOTS-c(human) acetate;Phloretin;GLUT inhibitor-1;4,6-O-Ethylidene-α-D-glucose;WZB117;GLUT1-IN-1;Lavendustin B;Avicularin;Rhoifolin;Fasentin;KL-11743;GLUT1-IN-2;DRB18

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