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RSL3
CAS No. : 1219810-16-8
Biological Activity：RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells.
Research Area：Cancer
Targets：Ferroptosis|Glutathione Peroxidase
Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;NF-κB Signaling Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Antioxidant Compound Library;Oxygen Sensing Compound Library;Ferroptosis Compound Library;Anti-Cancer Metabolism Compound Library;Targeted Diversity Library;Cuproptosis Compound Library;
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