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Opiorphin
CAS No. : 864084-88-8
Biological Activity：Opiorphin, an opioid peptide, is a potent enkephalin-inactivating zinc ectopeptidases in human inhibitor. Opiorphin inhibits two enkephalin-catabolizing ectoenzymes, human neutral ecto-endopeptidase, hNEP (EC 3.4.24.11) with an IC50 value of 11 μM, and human ecto-aminopeptidase, hAP-N (EC 3.4.11.2). Opiorphin displays potent analgesic activity by activating endogenous opioid-dependent transmission[2].
Research Area：Neurological Disease
Targets：Neprilysin
Related Small Molecules:TD-0212;Thiorphan;Phosphoramidon Disodium;Sacubitril-13C4 hemicalcium salt;Sacubitrilat;SCH 42495 racemate;NEP-IN-2;Thiorphan-d5;Racecadotril-d5;SCH-42354;Racecadotril;Sacubitril hemicalcium salt;NEP-In-1;Candoxatril;Sampatrilat;SQ28603
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