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NTQ1062
CAS No. : 2459489-66-6
Biological Activity：NTQ1062 is a potent and orally active Akt inhibitor with IC50s of 0.4 nM, 6.3 nM and 0.1 nM for Akt1, Akt2 and Akt3, respectively. NTQ1062 induces cell apoptosis and arrests the cell cycle at G0/G1 phase. NTQ1062 exhibits antiproliferation activity against various cancer cells. NTQ1062 exhibits potent antitumor efficacy in LNCap xenograft mouse model.
Research Area：Cancer
Targets：Akt
Related Small Molecules:Akt/NF-κB/JNK-IN-1;Cyclovirobuxine D;AKTide-2T;Sennidin A;MS98;PP2A Cancerous-IN-1;1,3-Dicaffeoylquinic acid;Artemisiane E;Artemisinin-d3;AS1949490;PI3K-IN-29;TD52 dihydrochloride;LM22B-10;AT13148;Pachymic acid;Glaucocalyxin A;PI3K/AKT-IN-2;INY-03-041;N-Oleoyl glycine;Triciribine;CCT128930;Chromeceptin;YS-49;AKT-IN-12;Licoricidin;A-443654;PI3K/AKT-IN-1;AKT-IN-9;GSK2110183 analog 1;MS5033
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