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Icenticaftor
CAS No. : 1334546-77-8
Biological Activity:Icenticaftor (QBW251) is an orally active CFTR channel potentiator, with EC50s of 79 nM and 497 nM for F508del and G551D CFTR, respectively. Icenticaftor can be used for chronic obstructive pulmonary disease (COPD) and cystic fibrosis research.
Research Area:Inflammation/Immunology
Targets:CFTR
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;
Related Small Molecules:PG01;CFTR corrector 8;CP-628006;SRI-37240;Urocortin III (mouse) (free acid);NJH-2-056;Elexacaftor;GlyH-101;Cavosonstat;Kobusin;GLPG1837;(R)-Posenacaftor sodium;GLPG2451;CFTR corrector 9;CFTR corrector 2;Vanzacaftor;CFTR corrector 4;Posenacaftor sodium;NJH-2-057;KM11060;Nesolicaftor;Galicaftor;Tezacaftor;PPQ-102;SRI-41315;CFTR corrector 6
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