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Iberdomide
CAS No. : 1323403-33-3
Biological Activity:Iberdomide (CC-220) is an orally active and potent cereblon (CRBN) E3 ligase modulator (CELMoD) with an IC50 of ~150 nM for cereblon-binding affinity. Iberdomide, a derivative of Thalidomide (HY-14658), has antitumor and immunostimulatory activities[2].
Research Area:Inflammation/Immunology|Cancer
Targets:Ligands for E3 Ligase|Apoptosis|Molecular Glues
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Ubiquitination Compound Library;Anti-COVID-19 Compound Library;Orally Active Compound Library;Anti-Blood Cancer Compound Library;Rare Diseases Drug Library;E3 Ligase Ligand Library;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;(S,R,S)-AHPC TFA;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;CRBN modulator-1;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine D
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