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Hydrocortisone hemisuccinate
CAS No. : 2203-97-6
Biological Activity：Hydrocortisone hemisuccinate (Hydrocortisone 21-hemisuccinate), a physiological glucocorticoid, is an orally active steroidal anti-inflammatory drug (SAID). Hydrocortisone hemisuccinate inhibits proinflammatory cytokine activity, with IC50s of 6.7 and 21.4 μM for IL-6 and IL-3, respectively. Hydrocortisone hemisuccinate can be used for the research of ulcerative colitis (UC)[2][3].
Research Area：Endocrinology|Metabolic Disease|Inflammation/Immunology
Targets：Glucocorticoid Receptor|Interleukin Related
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;FDA-Approved Drug Library;Drug Repurposing Compound Library;Differentiation Inducing Compound Library;Lipid Compound Library;Endocrinology Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Angiogenesis-Related Compound Library;Antidepressant Compound Library;Anti-Prostate Cancer Compound Library;Nuclear Receptor Compound Library;Non-steroidal Anti-Inflammatory Compound Library;
Related Small Molecules:AX-024;Deflazacort-D5;Ginsenoside F3;Perakizumab;PNRI-299;CTX-471;Ac-YVAD-CHO;Deucravacitinib;Mulberroside A;Glucocorticoid receptor agonist-2;NFAT Transcription Factor Regulator-1;IL-17A antagonist 1;Kansuinine B;Ginsenoside Rc;5(S)15(S)-DiHETE;IL-17A inhibitor 2;Anti-Mouse IL-1b Antibody;Raleukin;Ossirene
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