GW9508

For research use only. We do not sell to patients.

GW9508

CAS No. : 885101-89-3

Biological Activity:GW9508 is a potent and selective G protein-coupled receptors FFA1 (GPR40) and GPR120 agonist with pEC50s of 7.32 and 5.46, respectively. GW9508 shows ~100-fold selectivity for GPR40 over GPR120. GW9508 is inactive against other GPCRs, kinases, proteases, integrins and PPARs. GW9508 is a glucose-sensitive insulin secretagogue and an ATP-sensitive potassium (KATP) channels opener. Anti-inflammatory and anti-atherosclerotic activities[2][3][4].

Research Area:Metabolic Disease|Inflammation/Immunology|Cardiovascular Disease

Targets:Potassium Channel|Free Fatty Acid Receptor

Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library; Kinase Inhibitor Library;Membrane Transporter/Ion Channel Compound Library;Anti-diabetic Compound Library;Anti-Cardiovascular Disease Compound Library;Neuroprotective Compound Library;Lipid Metabolism Compound Library ;Targeted Diversity Library;Potassium Channel Compound Library;Human Metabolite Library;

Related Small Molecules:GW-1100;Kv3 modulator 2;Brompheniramine-d6 maleate;Pinacidil;AMP-PNP tetralithium;IK1 inhibitor PA-6;Grifolic acid;VU590;Domiphen bromide;Mesoridazine benzenesulfonate;Ginsenoside Rb2;Tetrandrine;20(S)-Ginsenoside Rg3;(S)-(+)-Modafinic acid-d5;Ketanserin;PE 22-28;Ifenprodil tartrate;Brompheniramine maleate;AP5;L-Palmitoylcarnitine-d3 hydrochloride;Phe-Met-Arg-Phe amide trifluoroacetate;Mitiglinide;Flupirtine-d4 hydrochloride

Trending products:Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides

About Us:

  • MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use;
  • Structurally and synthetically diverse biologically active compounds;
  •  roduct quality is the key to our success and we take pride in offering only the highest-grade products.;
  • We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.;
  • Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.;
  • Structurally and synthetically diverse biologically active compounds;

  • Customized order volume ranging from milligrams to kilograms scale;
  • We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.

50K Diversity Library
Top Publications Citing Use of MCE Products
Recombinant Proteins
magnetic-beads