Chlorothiazide

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Chlorothiazide

CAS No. : 58-94-6

Biological Activity:Chlorothiazide is a diuretic and antihypertensive. (IC50=3.8 mM)
Target: Others
Chlorothiazide sodium (Diuril) is a diuretic used within the hospital setting or for personal use to manage excess fluid associated with congestive heart failure. It is also used as an antihypertensive.
Most often taken in pill form, it is usually taken orally once or twice a day. In the ICU setting, chlorothiazide is given to diurese a patient in addition to furosemide (Lasix). Working in a separate mechanism than furosemide, and absorbed enterically as a reconstituted suspension administered through a nasogastric tube (NG tube), the two drugs potentiate one another.

Research Area:Cardiovascular Disease

Targets:Others

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