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RO4929097
CAS No. : 847925-91-1
Biological Activity：RO4929097 (RG-4733) is a γ secretase inhibitor with IC50 of 4 nM, inhibiting cellular processing of Aβ40 and Notch with EC50 of 14 nM and 5 nM, respectively.
Research Area：Neurological Disease|Cancer
Targets：Notch|γ-secretase
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Neuronal Signaling Compound Library;Stem Cell Signaling Compound Library;Wnt/Hedgehog/Notch Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Antiviral Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Differentiation Inducing Compound Library;Reprogramming Compound Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Neurodegenerative Disease-related Compound Library;Angiogenesis-Related Compound Library;Transcription Factor-Targeted Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:γ-Secretase modulator 4;ELN318463;ZLDI-8;Crenigacestat;Aβ42-IN-1 free base;Fosciclopirox;FLI-06;JNJ-40418677;gamma-secretase modulator 3;γ-Secretase modulator 11 hydrochloride;γ-Secretase modulator 12;JI051;Aβ42-IN-2;Demcizumab;DAPT (GMP);Notch inhibitor 1;BPN-15606;Tarextumab;Notch 1 TFA;Bruceine D;LY-411575 (isomer 3);Psoralidin;BMS 433796;YO-01027 (GMP);BI-1408
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