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CAS No. : 2366269-23-8

Biological Activity:Palbociclib-propargyl is a ligand for target protein CDK6 for PROTAC, and binds to CRBN ligand via a PEG linker to make a PROTAC CP-10. CP-10 shows a DC50 of 2.1 nM for CDK6.

Research Area:Cancer

Targets:Ligands for Target Protein for PROTAC

Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Anti-Cancer Compound Library;Covalent Screening Library;Target Protein Ligand Library;

Related Small Molecules:BI-4464;PROTAC BRD4 ligand-2;PROTAC BRD9-binding moiety 1 hydrochloride;PROTAC IRAK4 ligand-1;Apcin-A;Ipatasertib-NH2 dihydrochloride;SirReal1-O-propargyl;PD0325901-O-C2-dioxolane;CDK9-IN-10;TSPO ligand-1;SLF TFA;PROTAC Bcl-xL ligand-1;ATRA-hydroxyimino;HG-7-85-01-Decyclopropane;MAK683-CH2CH2COOH;DUPA;Abemaciclib metabolite M18;PROTAC PTK6 ligand-1;PROTAC BRD9-binding moiety 5;SLF-amido-C2-COOH;AP1867-3-(aminoethoxy);SMARCA-BD ligand 1 for Protac dihydrochloride;Ch55-O-C3-NH2;PROTAC PARP/EGFR ligand 1;PROTAC BET-binding moiety 1

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