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CAS No. : 162641-16-9

Biological Activity:HQL-79, a potent, selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, highly selectively inhibits the synthesis of PGD2, and acts as an anti-allergic agent, with a Kd of 0.8 μM and an IC50 of 6 μM. Shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS.

Research Area:Inflammation/Immunology

Targets:PGE synthase

Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Orally Active Compound Library;

Related Small Molecules:Bismuth Subsalicylate;PGS-IN-1;Suprofen;Ethyl Caffeate;HPGDS inhibitor 1;Limaprost-d3;Sinensetin-d3;Vipoglanstat;Isofezolac;HPGDS inhibitor 2;Sinensetin;Cafestol;BRP-201;Zaloglanstat;CAY10526;Clopirac;mPGES-1-IN-1;hPGDS-IN-1;PF-9184;Pranoprofen;mPGES1-IN-3;YS121;Zomepirac sodium salt;Desoxo-narchinol A;AT-56;Dehydroevodiamine

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