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GNE-4997
CAS No. : 1705602-02-3
Biological Activity：GNE-4997 is a potent and selective interleukin-2-inducible T-cell kinase (ITK) inhibitor with a Ki of 0.09 nM, and the correlation between the basicity of solubilizing elements in GNE-4997 and off-target antiproliferative effects reduces cytotoxicity.
Research Area：Inflammation/Immunology
Targets：Itk
Related Small Molecules:ITK antagonist;Vecabrutinib;EGFR-IN-40;GSK-2250665A;ITK/TRKA-IN-1;ITK inhibitor 2;ITK inhibitor 5;PF-06465469;PRN694;BI-1622;BMS-509744;ITK inhibitor 6
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