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CAS No. : 603987-35-5

Biological Activity:E6201 (ER-806201) is an ATP-competitive dual kinase inhibitor of MEK1 and FLT3. E6201 inhibits MEK1- induced ERK2 phosphorylation with an IC50 value of 5.2 nM, MKK4-induced JNK phosphorylation with an IC50 value of 91 nM, and MKK6-induced p38 MAPK phosphorylation with an IC50 value of 19 nM. Anti-tumor and anti-psoriasis efficacy[2].

Research Area:Cancer


Related Small Molecules:Avutometinib;AT9283;(E/Z)-Zotiraciclib;Crotonoside;Cobimetinib racemate;FLT3-IN-13;PDGFRα/FLT3-ITD-IN-2;FLT3/CDK4-IN-1;EBI-1051;HP1142;ENMD-2076 Tartrate;CHMFL-EGFR-202;ATH686;AZD2932;AKN-028 acetate;BI-847325;FLT3-IN-3;UNC2025 hydrochloride;Tandutinib;MAP855;Gilteritinib-d8;PF 477736;(R)-3-Hydroxy Midostaurin;BSc5371

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