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Clindamycin hydrochloride monohydrate
CAS No. : 58207-19-5
Biological Activity:Clindamycin hydrochloride monohydrate is an oral protein synthesis inhibitory agent that has the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin hydrochloride monohydrate resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin hydrochloride monohydrate decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla).
Research Area:Infection|Cancer
Targets:Bacterial|Antibiotic
Related Small Molecules:Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Monascorubrin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;Antibacterial agent 99;Vidarabine monohydrate;Nafcillin;Antitubercular agent-28;Ochromycinone;Staurosporine;Nucleocidin;(±)-Leucine-13C-1;Ciclopirox-d11;Ciclopirox olamine;Clotrimazole-d5;SQ109;(R)-Camptothecin-d5
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